1. From fibrositis to fibromyalgia to nociplastic pain: how rheumatology helped get us here and where do we go from here?
   2024/08/07 by Daniel J Clauw, Daniel J. Clauw · 23 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Anesthesia #Chronic pain #Fibromyalgia #Fibromyalgia and Chronic Fatigue Syndrome Research #Internal medicine #Medicine #Musculoskeletal pain and rehabilitation #Myofascial pain diagnosis and treatment #Neuropathic pain #Nociception #Physical therapy #Receptor #Rheumatology
2. Paclitaxel in vitro reversibly sensitizes the excitability of IB4(−) and IB4(+) sensory neurons from male and female rats
   2022/02/01 by Eva Villalba‐Riquelme, Roberto de la Torre‐Martínez, Asia Fernández‐Carvajal +1 · 11 citations
   Medicine · Neuroscience · #Biology #Cancer Treatment and Pharmacology #Cancer, Stress, Anesthesia, and Immune Response #Chemotherapy #Chemotherapy-induced peripheral neuropathy #Dorsal root ganglion #Endocrinology #Immunology #Internal medicine #Medicine #Neuroscience #Nociception #Nociceptor #Paclitaxel #Pain Mechanisms and Treatments #Peripheral neuropathy #Pharmacology #Sensitization #Sensory neuron #Sensory system #TRPM8 #TRPV1 #Transient receptor potential channel
3. Neural and sociocultural mediators of ethnic differences in pain
   2020/02/03 by Elizabeth A. Reynolds Losin, Choong-Wan Woo, Choong‐Wan Woo +5 · 27 citations
   Medicine · Neuroscience · Psychology · #Chronic pain #Clinical psychology #Context (archaeology) #Ethnic group #Functional magnetic resonance imaging #Internal medicine #Medicine #Musculoskeletal pain and rehabilitation #Neuroimaging #Neuroscience #Nociception #Pain Management and Placebo Effect #Pain Mechanisms and Treatments #Pain catastrophizing #Psychiatry #Psychology
4. Evidence of opioid-induced hyperalgesia in clinical populations after chronic opioid exposure: a systematic review and meta-analysis
   2018/10/25 by C. Higgins, Cassie Higgins, Blair H. Smith +2 · 1 citation
   Medicine · #Biology #Chronic pain #Hyperalgesia #Internal medicine #MEDLINE #Medicine #Meta-analysis #Nociception #Opioid #Opioid Use Disorder Treatment #Opioid addiction #Pain Management and Opioid Use #Pain Mechanisms and Treatments #Psychiatry #Systematic review
5. Nicotine deprivation increases pain intensity, neurogenic inflammation, and mechanical hyperalgesia among daily tobacco smokers.
   2018/05/21 by Joseph W. Ditre, Emily L. Zale, Lisa R. LaRowe +3 · 25 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · Psychology · #Anesthesia #Fibromyalgia and Chronic Fatigue Syndrome Research #Hyperalgesia #Inflammation #Internal medicine #Medicine #Neuroscience #Nicotine #Nicotinic Acetylcholine Receptors Study #Nociception #Psychology #Smoking Behavior and Cessation
6. Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons
   2018/04/18 by Rahul Dhandapani, Cynthia M. Arokiaraj, Francisco J. Taberner +15 · 2 citations
   Medicine · Neuroscience · #Allodynia #Anesthesia #Biology #Hyperalgesia #Internal medicine #Ion Channels and Receptors #Medicine #Nerve injury #Neurobiology and Insect Physiology Research #Neuropathic pain #Neuroscience #Neurotrophic factors #Nociception #Nociceptor #Optogenetics #Pain Mechanisms and Treatments #Photoablation #Population #Receptor #Sensory system #Tropomyosin receptor kinase B
7. Analgesic mechanisms of gabapentinoids and effects in experimental pain models: a narrative review
   2018/04/12 by M. Chincholkar · 27 citations
   Medicine · Neuroscience · Psychology · #Analgesic #Anesthesia #Anesthesia and Pain Management #Central nervous system #Chronic pain #Dorsal root ganglion #Internal medicine #Medicine #Neuropathic pain #Neuropeptides and Animal Physiology #Neuroscience #Neurotransmitter #Nociception #Pain Mechanisms and Treatments #Pharmacology #Pregabalin #Psychology #Receptor #Sensory system
8. Neuroinflammation and Central Sensitization in Chronic and Widespread Pain
   2018/02/16 by Ru‐Rong Ji, Ru-Rong Ji, Andrea G. Nackley +4 · 39 citations
   Medicine · Neuroscience · Psychology · #Allodynia #Central nervous system #Chemokine #Chronic pain #Hyperalgesia #Immune system #Immunology #Inflammation #Internal medicine #Medicine #Microglia #Neuroinflammation #Neuropeptides and Animal Physiology #Neuroscience #Nociception #Pain Mechanisms and Treatments #Proinflammatory cytokine #Psychology #Receptor #Sensitization #Stress Responses and Cortisol
9. Antiallodynic and antihyperalgesic activity of new 3,3-diphenyl-propionamides with anticonvulsant activity in models of pain in mice
   2017/12/17 by Anna Rapacz, Jolanta Obniska, Paulina Koczurkiewicz +8 · 10 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Analgesic #Anesthesia #Anticonvulsant #Cancer Treatment and Pharmacology #Chemistry #Chronic pain #Diabetes mellitus #Endocrinology #Epilepsy #Internal medicine #Medicine #Neuropathic pain #Nociception #Pain Mechanisms and Treatments #Peripheral neuropathy #Pharmacological Receptor Mechanisms and Effects #Pharmacology #Pregabalin #Receptor
10. Sex differences and estradiol involvement in hyperalgesia and allodynia in an experimental model of fibromyalgia
    2017/11/08 by Alberto Hernandez-Leon, Alberto Hernández-León, Yarim Elideth De la Luz-Cuellar +5 · 18 citations
    Medicine · #Allodynia #Endocrinology #Estrogen #Estrous cycle #Fibromyalgia #Fibromyalgia and Chronic Fatigue Syndrome Research #Hormone #Hyperalgesia #Internal medicine #Medicine #Menopause #Musculoskeletal pain and rehabilitation #Nociception #Ovariectomized rat #Pain Mechanisms and Treatments #Receptor #Reserpine
11. Impaired Pain-evoked Analgesia after Nerve Injury in Rats Reflects Altered Glutamate Regulation in the Locus Coeruleus
    2015/08/05 by Masafumi Kimura, Takashi Suto, Carlos E. Morado-Urbina +4 · 25 citations
    Medicine · Neuroscience · #Anesthesia #Biology #Central nervous system #Endocrinology #Glutamate receptor #Internal medicine #Locus coeruleus #Medicine #Metabotropic glutamate receptor #Nerve injury #Neuropathic pain #Neuroscience #Neuroscience and Neuropharmacology Research #Nociception #Noxious stimulus #Pain Management and Treatment #Pain Mechanisms and Treatments #Pharmacology #Receptor #Spinal cord #Stimulation
12. A potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist, MK-8825, inhibits responses to nociceptive trigeminal activation: Role of CGRP in orofacial pain
    2015/05/14 by Marcela Romero‐Reyes, Marcela Romero-Reyes, Vanessa Pardi +1 · 25 citations
    Chemistry · Medicine · Neuroscience · Psychology · #Antagonist #Calcitonin #Calcitonin gene-related peptide #Chemistry #Endocrinology #Internal medicine #Medicine #Migraine and Headache Studies #Neuropeptide #Neuroscience #Nociception #Orofacial pain #Pain Mechanisms and Treatments #Pharmacology #Psychology #Receptor #Surgery #Trigeminal Neuralgia and Treatments #Trigeminal ganglion
13. A critical evaluation of the trigger point phenomenon
    2014/12/03 by John Quintner, Geoffrey M. Bove, Milton Cohen · 1 citation
    Biochemistry, Genetics and Molecular Biology · Health Professions · Medicine · Neuroscience · Psychology · #Myofascial pain diagnosis and treatment #Therapeutic Uses of Natural Elements #Acupuncture Treatment Research Studies #Medicine #Myofascial pain syndrome #Suspect #Pathological #Myofascial pain #Nociception #Intensive care medicine #Neuroscience #Epistemology #Physical medicine and rehabilitation #Physical therapy #Pathology #Alternative medicine #Internal medicine #Psychology
14. The noradrenergic pain regulation system: A potential target for pain therapy
    2013/03/13 by Antti Pertovaara · 28 citations
    Medicine · Neuroscience · Psychology · #Adrenergic #Anatomy #Anesthesia #Axon #Chronic pain #Dopamine #Excitatory postsynaptic potential #Hormonal and reproductive studies #Inhibitory postsynaptic potential #Internal medicine #Medicine #Neuropathic pain #Neuropeptides and Animal Physiology #Neuroscience #Nociception #Nociceptor #Norepinephrine #Pain Mechanisms and Treatments #Peripheral #Psychology #Receptor #Spinal cord
15. Hypnotic modulation of pain perception and of brain activity triggered by nociceptive laser stimuli
    2012/02/22 by Elia Valentini, Viviana Betti, Li Hu +2 · 15 citations
    Medicine · Neuroscience · Psychology · #Cognitive psychology #Hyperalgesia #Hypnotic #Hypoalgesia #Medicine #Neuroscience #Nociception #Pain Management and Placebo Effect #Pain Mechanisms and Treatments #Pediatric Pain Management Techniques #Perception #Psychiatry #Psychology #Sensory system #Somatosensory system
16. Nociceptors: the sensors of the pain pathway
    2010/11/01 by Adrienne E. Dubin, Ardem Patapoutian · 1 citation
    Medicine · Neuroscience · #Pain Mechanisms and Treatments #Ion Channels and Receptors #Neurobiology and Insect Physiology Research #Nociceptor #Neuroscience #Sensory system #Nociception #Medicine #Biology #Receptor #Internal medicine
17. Excitation and sensitization of nociceptors by bradykinin: what do we know?
    2009/04/25 by Kazue Mizumura, Takeshi Sugiura, Kimiaki Katanosaka +2 · 27 citations
    Chemistry · Medicine · Neuroscience · #Biochemistry #Biology #Biophysics #Bradykinin #Cell biology #Chemistry #Endocrinology #Endogeny #Hyperalgesia #Internal medicine #Ion Channels and Receptors #Medicine #Neurobiology and Insect Physiology Research #Neuroscience #Nociception #Nociceptor #Pain Mechanisms and Treatments #Pharmacology #Receptor #Sensitization #Stimulation #TRPV1 #Transient receptor potential channel
18. Joint pain
    2009/04/10 by Hans‐Georg Schaible, Hans-Georg Schaible, Frank Richter +8 · 25 citations
    Medicine · Neuroscience · Psychology · #Arthritis #Central sensitization #Chronic pain #Healthcare and Venom Research #Hyperalgesia #Immunology #Inflammation #Internal medicine #Joint pain #Medicine #Neuroscience #Nociception #Nociceptor #Osteoarthritis Treatment and Mechanisms #Pain Mechanisms and Treatments #Pathological #Psychology #Receptor #Sensitization #Stimulation
19. The role of learning in nocebo and placebo effects
    2008/03/27 by Luana Colloca, Monica Sigaudo, Fabrizio Benedetti · 4 citations
    Neuroscience · Medicine · Psychology · #Pain Management and Placebo Effect #Pain Mechanisms and Treatments #Empathy and Medical Education #Nocebo #Nocebo Effect #Placebo #Hyperalgesia #Conditioning #Allodynia #Anesthesia #Psychology #Medicine #Classical conditioning #Visual analogue scale #Audiology #Nociception #Internal medicine
20. Nocebo hyperalgesia: how anxiety is turned into pain
    2007/10/01 by Luana Colloca, Fabrizio Benedetti · 1 citation
    Neuroscience · Medicine · Psychology · #Pain Management and Placebo Effect #Pain Mechanisms and Treatments #Acupuncture Treatment Research Studies #Nocebo #Nocebo Effect #Hyperalgesia #Anxiety #Cholecystokinin #Neurochemical #Psychology #Placebo #Neuroscience #Mindfulness #Medicine #Anesthesia #Nociception #Psychotherapist #Psychiatry #Internal medicine
21. When words are painful: Unraveling the mechanisms of the nocebo effect
    2007/03/27 by F. Benedetti, Francesco Benedetti, Michele Lanotte +5 · 4 citations
    Medicine · Neuroscience · Psychology · #Anxiety #Clinical psychology #Disease #Hyperalgesia #Internal medicine #Mechanism (biology) #Medicine #Neurochemical #Neuroscience #Neuroscience, Education and Cognitive Function #Nocebo #Nocebo Effect #Nociception #Pain Management and Placebo Effect #Pain Mechanisms and Treatments #Placebo #Psychiatry #Psychology #Psychotherapist
22. Peri-sciatic administration of recombinant rat TNF-α induces mechanical allodynia via upregulation of TNF-α in dorsal root ganglia and in spinal dorsal horn: The role of NF-kappa B pathway
    2007/03/24 by Xu-Hong Wei, Xu‐Hong Wei, Ying Zang +8 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Allodynia #Anatomy #Anesthesia #Chemistry #Downregulation and upregulation #Endocrinology #Hyperalgesia #Internal medicine #Medicine #Musculoskeletal pain and rehabilitation #Myofascial pain diagnosis and treatment #Nociception #Pain Mechanisms and Treatments #Pathology #Receptor #Sciatic nerve #Sciatic nerve injury #Spinal cord #Tumor necrosis factor alpha
23. Social Modulation of Pain as Evidence for Empathy in Mice
    2006/06/30 by Dale J. Langford, Sara E. Crager, Zarrar Shehzad +6 · 5 citations
    Psychology · Neuroscience · Medicine · #Neuroendocrine regulation and behavior #Stress Responses and Cortisol #Olfactory and Sensory Function Studies #Empathy #Nociception #Noxious stimulus #Stimulus (psychology) #Psychology #Neuroscience #Medicine #Internal medicine #Psychiatry #Receptor #Psychotherapist
24. Spinal cord injury triggers sensitization of wide dynamic range dorsal horn neurons in segments rostral to the injury
    2005/08/04 by Haijun Zhang, Wenrui Xie, Yikuan Xie · 14 citations
    Medicine · Neuroscience · Psychology · #Allodynia #Anesthesia #Botulinum Toxin and Related Neurological Disorders #Central nervous system #Chronic pain #Endocrinology #Hyperalgesia #Internal medicine #Lesion #Medicine #Nerve injury #Neuropathic pain #Neuroscience #Nociception #Pain Mechanisms and Treatments #Pathology #Psychology #Spinal Cord Injury Research #Spinal cord #Spinal cord injury
25. Spinal nerve ligation increases α2-adrenergic receptor G-protein coupling in the spinal cord
    2005/02/17 by Carsten Bantel, James C. Eisenach, Frederic Duflo +3 · 23 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Adrenergic #Adrenergic receptor #Agonist #Antagonist #Biology #Chemistry #Clonidine #Endocrinology #Internal medicine #Ion channel regulation and function #Medicine #Musculoskeletal pain and rehabilitation #Neuropathic pain #Neuroscience #Nociception #Pain Mechanisms and Treatments #Pharmacology #Prazosin #Rauwolscine #Receptor #Spinal cord
26. The behavioral and neuroanatomical effects of IB4-saporin treatment in rat models of nociceptive and neuropathic pain
    2004/10/28 by Jason Tarpley, Jason W. Tarpley, Martin Köhler +2 · 26 citations
    Medicine · Neuroscience · Pharmacology, Toxicology and Pharmaceutics · Psychology · #Allodynia #Anesthesia #Endocrinology #Hyperalgesia #Immunology #Immunotoxin #Internal medicine #Medicine #Nerve injury #Neuropathic pain #Neuropeptide #Neuropeptides and Animal Physiology #Neuroscience #Nociception #Pain Mechanisms and Treatments #Peripheral nerve injury #Pharmacological Effects of Natural Compounds #Psychology #Receptor #Saporin #Sciatic nerve #Spinal cord #Substance P
27. Vicarious responses to pain in anterior cingulate cortex: Is empathy a multisensory issue?
    2004/06/01 by India Morrison, Donna M. Lloyd, Donna Lloyd +3 · 8 citations
    Medicine · Neuroscience · Psychology · #Action Observation and Synchronization #Anterior cingulate cortex #Aversive Stimulus #Cognition #Cognitive psychology #Empathy #Functional magnetic resonance imaging #Medicine #Neural and Behavioral Psychology Studies #Neuroscience #Nociception #Noxious stimulus #Pain Management and Placebo Effect #Psychiatry #Psychology #Somatosensory system #Stimulation #Stimulus (psychology) #Transcranial magnetic stimulation
28. Clinical usefulness of laser-evoked potentials
    2003/12/01 by Rolf-Detlef Treede, Rolf‐Detlef Treede, Jürgen Lorenz +1 · 3 citations
    Medicine · Neuroscience · Psychology · #Brainstem #Medial lemniscus #Medicine #Neurology and Historical Studies #Neuroscience #Nociception #Pain Mechanisms and Treatments #Psychology #Psychosomatic Disorders and Their Treatments #Somatosensory evoked potential #Somatosensory system #Spinothalamic tract #Thalamus
29. Do fishes have nociceptors? Evidence for the evolution of a vertebrate sensory system
    2003/06/07 by Lynne U. Sneddon, Victoria A. Braithwaite, M. J. Gentle · 3 citations
    Agricultural and Biological Sciences · Medicine · Neuroscience · Psychology · #Anatomy #Biology #Diffuse noxious inhibitory control #Internal medicine #Meat and Animal Product Quality #Medicine #Neurobiology and Insect Physiology Research #Neuroscience #Nociception #Nociceptor #Noxious stimulus #Psychology #Receptor #Reflex #Sensory system #Stimulus (psychology)
30. Thermal avoidance in Caenorhabditis elegans : An approach to the study of nociception
    1999/08/31 by Nicole Wittenburg, Ralf Baumeister · 2 citations
    Biochemistry, Genetics and Molecular Biology · Neuroscience · Psychology · #Aversive Stimulus #Avoidance behaviour #Biology #Caenorhabditis elegans #Circadian rhythm and melatonin #Escape response #Gene #Genetics #Genetics, Aging, and Longevity in Model Organisms #Neurobiology and Insect Physiology Research #Neuroscience #Nociception #Noxious stimulus #Psychology #Reflex #Sensory system #Stimulus (psychology)

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