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Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

2021/02/04 by Hyuna Sung, Jacques Ferlay, Adalberto M. Filho +5 · 113,535 citations
Medicine · #Breast cancer #Cancer #Colorectal Cancer Screening and Detection #Colorectal cancer #Demography #Global Cancer Incidence and Screening #Incidence (geometry) #Internal medicine #Lung cancer #Medicine #Mortality rate #Multiple and Secondary Primary Cancers #Oncology #Prostate cancer #Skin cancer #Stomach cancer

paper · pdf · doi:10.3322/caac.21660

published in CA A Cancer Journal for Clinicians 71(3), 209-249 (Wiley)

openalex publication_date 2021/02/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05

Abstract

This article provides an update on the global cancer burden using the GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer. Worldwide, an estimated 19.3 million new cancer cases (18.1 million excluding nonmelanoma skin cancer) and almost 10.0 million cancer deaths (9.9 million excluding nonmelanoma skin cancer) occurred in 2020. Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%), followed by lung (11.4%), colorectal (10.0 %), prostate (7.3%), and stomach (5.6%) cancers. Lung cancer remained the leading cause of cancer death, with an estimated 1.8 million deaths (18%), followed by colorectal (9.4%), liver (8.3%), stomach (7.7%), and female breast (6.9%) cancers. Overall incidence was from 2-fold to 3-fold higher in transitioned versus transitioning countries for both sexes, whereas mortality varied <2-fold for men and little for women. Death rates for female breast and cervical cancers, however, were considerably higher in transitioning versus transitioned countries (15.0 vs 12.8 per 100,000 and 12.4 vs 5.2 per 100,000, respectively). The global cancer burden is expected to be 28.4 million cases in 2040, a 47% rise from 2020, with a larger increase in transitioning (64% to 95%) versus transitioned (32% to 56%) countries due to demographic changes, although this may be further exacerbated by increasing risk factors associated with globalization and a growing economy. Efforts to build a sustainable infrastructure for the dissemination of cancer prevention measures and provision of cancer care in transitioning countries is critical for global cancer control.

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