Glenda Kohlhagen
- Synthesis of New Indeno[1,2-c]isoquinolines: Cytotoxic Non-Camptothecin Topoisomerase I Inhibitors
2000/09/19 by Mark Cushman, Muthusamy Jayaraman, Jeffrey A. Vroman +5 · 15 citations
Biochemistry, Genetics and Molecular Biology · Pharmacology, Toxicology and Pharmaceutics · #Cancer therapeutics and mechanisms #Bioactive Compounds and Antitumor Agents #Synthesis and bioactivity of alkaloids
- Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Topoisomerase I Inhibitors Featuring Polyamine Side Chains on the Lactam Nitrogen
2003/11/21 by Muthukaman Nagarajan, Xiangshu Xiao, Smitha Antony +3 · 11 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Cancer therapeutics and mechanisms #Synthesis and Biological Evaluation #Synthesis and Biological Activity
- Synthesis and Evaluation of Indenoisoquinoline Topoisomerase I Inhibitors Substituted with Nitrogen Heterocycles
2006/09/26 by Muthukaman Nagarajan, Andrew Morrell, Alexandra Ioanoviciu +6 · 11 citations
Biochemistry, Genetics and Molecular Biology · Pharmacology, Toxicology and Pharmaceutics · #Cancer therapeutics and mechanisms #Bioactive Compounds and Antitumor Agents #Synthesis and bioactivity of alkaloids
- Cellular Topoisomerase I Inhibition and Antiproliferative Activity by MJ-III-65 (NSC 706744), an Indenoisoquinoline Topoisomerase I Poison
2004/11/06 by Smitha Antony, Glenda Kohlhagen, Keli Agama +6 · 6 citations
Biochemistry, Genetics and Molecular Biology · Pharmacology, Toxicology and Pharmaceutics · #Bioactive Compounds and Antitumor Agents #Cancer therapeutics and mechanisms #Synthesis and bioactivity of alkaloids
- Synthesis and Biological Evaluation of Bisindenoisoquinolines as Topoisomerase I Inhibitors
2006/07/28 by Muthukaman Nagarajan, Andrew Morrell, Smitha Antony +8 · 4 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Cancer therapeutics and mechanisms #Synthesis and biological activity #Bioactive Compounds and Antitumor Agents