- Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy Adults
2026/02/01 by Pablo Salcedo, Donna A. Volpe, Anik Chaturbedi +10 · 1 citation
Medicine · Pharmacology, Toxicology and Pharmaceutics · #Cannabidiol #Cannabis and Cannabinoid Research #Citalopram #Drug #Drug interaction #Forensic Toxicology and Drug Analysis #Morphine #Pharmacokinetics #Substance Abuse Treatment and Outcomes
- Opioids in patients with COPD and refractory dyspnea: literature review and design of a multicenter double blind study of low dosed morphine and fentanyl (MoreFoRCOPD)
2021/09/10 by Marlies van Dijk, Kris Mooren, Jan Willem van den Berg +7 · 11 citations
Medicine · #Chronic Obstructive Pulmonary Disease (COPD) Research #Respiratory and Cough-Related Research #Obstructive Sleep Apnea Research #Medicine #Placebo #Fentanyl #COPD #Randomized controlled trial #Anesthesia #Quality of life (healthcare) #Clinical endpoint #Morphine #Clinical trial #Refractory (planetary science) #Internal medicine
- Analgesic effect of morphine and tramadol in standard toxicity assays in mice injected with venom of the snake Bothrops asper
2018/09/27 by Cristina Herrera, Fiona Bolton, Ana Silvia Arias +3 · 32 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Analgesic #Anesthesia #Antivenom #Biology #Bothrops #Healthcare and Venom Research #Internal medicine #Medicine #Morphine #Pain Mechanisms and Treatments #Pharmacology #Snake venom #Toxicity #Tramadol #Venom #Venomous Animal Envenomation and Studies
- Postoperative opioid prescribing practices and the impact of the hydrocodone schedule change
2018/08/06 by Wen Hui Tan, Sara Feaman, Laurel Milam +4 · 17 citations
Medicine · #Analgesic #Anesthesia #Anesthesia and Pain Management #Hydrocodone #Internal medicine #Medical prescription #Medicine #Morphine #Opioid #Opioid Use Disorder Treatment #Oxycodone #Pain Management and Opioid Use #Pharmacology #Tramadol
- Association of the OPRM1 and COMT genes’ polymorphisms with the efficacy of morphine in Tunisian cancer patients: Impact of the high genetic heterogeneity in Tunisia?
2016/05/18 by Imen Chatti, Isabelle Creveaux, Jean-Baptiste Woillard +10 · 13 citations
Medicine · Neuroscience · #Biology #Cancer #Cancer pain #Cancer, Stress, Anesthesia, and Immune Response #Catechol-O-methyl transferase #Gene #Genetic association #Genetics #Genotype #Gynecology #Haplotype #Internal medicine #Medicine #Morphine #Neuropeptides and Animal Physiology #Oncology #Opioid #Pain Management and Opioid Use #Receptor #SNP #Single-nucleotide polymorphism #rs4680
- The on- and off-target effects of morphine in acute coronary syndrome: A narrative review
2016/04/16 by Cian P. McCarthy, Kieran V. Mullins, Sunjeet Sidhu +3 · 37 citations
Medicine · #Acute Myocardial Infarction Research #Acute coronary syndrome #Adverse effect #Alternative medicine #Analgesic #Anesthesia #Cardiac Arrest and Resuscitation #Clinical trial #Heart Failure Treatment and Management #Intensive care medicine #Internal medicine #Medicine #Morphine #Myocardial infarction #Observational study #Opioid #Oxycodone #Placebo #Randomized controlled trial
- Current Evidence for Spinal Opioid Selection in Postoperative Pain
2014/07/11 by Borja Mugabure Bujedo · 37 citations
Medicine · #Pain Management and Opioid Use #Anesthesia and Pain Management #Opioid Use Disorder Treatment #Medicine #Hydromorphone #Alfentanil #Sufentanil #Opioid #Anesthesia #Analgesic #Fentanyl #Morphine #Onset of action #Intensive care medicine #Internal medicine
- Pharmacokinetics of acetaminophen, codeine, and the codeine metabolites morphine and codeine-6-glucuronide in healthy Greyhound dogs
2009/05/20 by Butch KuKanich · 65 citations
Veterinary · Medicine · Pharmacology, Toxicology and Pharmaceutics · Chemistry · #Veterinary Pharmacology and Anesthesia #Pain Mechanisms and Treatments #Drug-Induced Hepatotoxicity and Protection #Codeine #Acetaminophen #Pharmacokinetics #Bioavailability #Morphine #Pharmacology #Oral administration #Glucuronide #Chemistry #Urine #Medicine #Biochemistry
- Opioids Switching with Transdermal Systems in Chronic Cancer Pain
2009/05/07 by Caterina Aurilio, Maria Caterina Pace, Vincenzo Pota +4 · 38 citations
Medicine · #Pain Management and Opioid Use #Opioid Use Disorder Treatment #Pain Mechanisms and Treatments #Medicine #Fentanyl #Buprenorphine #Tolerability #Transdermal #Adverse effect #Opioid #Anesthesia #Cancer pain #Chronic pain #Morphine #Internal medicine #Cancer #Pharmacology #Physical therapy
- Endogenous formation of morphine in human cells
2004/09/21 by Chotima Poeaknapo, Jürgen Schmidt, Matthias Brandsch +2 · 105 citations
Chemistry · Medicine · Neuroscience · Pharmacology, Toxicology and Pharmaceutics · #Alkaloid #Alkaloids: synthesis and pharmacology #Benzylisoquinoline #Berberine and alkaloids research #Biochemistry #Biology #Biosynthesis #Botany #Cell culture #Chemistry #Codeine #Endogeny #Enzyme #Morphine #Neuroblastoma #Neuropeptides and Animal Physiology #Opium #Papaver #Papaveraceae #Pharmacology #SH-SY5Y #Stereochemistry #Thebaine
- The Safety and Efficacy of a Fentanyl Patient-Controlled Transdermal System for Acute Postoperative Analgesia: A Multicenter, Placebo-Controlled Trial
2004/02/01 by Jacques E. Chelly, Jeffrey A. Grass, Timothy W. Houseman +2 · 137 citations
Medicine · #Pain Management and Opioid Use #Opioid Use Disorder Treatment #Anesthesia and Pain Management #Fentanyl #Medicine #Placebo #Transdermal #Anesthesia #Visual analogue scale #Patient-controlled analgesia #Morphine #Randomized controlled trial #Clinical trial #Surgery #Internal medicine
- Dihydroetorphine: A Potent Analgesic: Pharmacology, Toxicology, Pharmacokinetics, and Clinical Effects
2002/12/01 by Satoshi Ohmori, Yasunori Morimoto · 20 citations
Medicine · Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Pain Mechanisms and Treatments #Chemical synthesis and alkaloids #Plant-based Medicinal Research #Pharmacology #Analgesic #Medicine #Pharmacokinetics #Opioid #Morphine #Agonist #Anesthesia #Receptor #Internal medicine
- Synthesis of (−)-Morphine
2002/09/28 by Douglass F. Taber, Timothy D. Neubert, Arnold L. Rheingold · 117 citations
Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Aldehyde #Alkaloids: synthesis and pharmacology #Cancer Treatment and Pharmacology #Catalysis #Chemical synthesis and alkaloids #Chemistry #Cyclopentene #Enone #Hydrolysis #Intramolecular force #Morphine #Organic chemistry #Stereochemistry #Tetralone
- Endocytosis of the Mu Opioid Receptor Reduces Tolerance and a Cellular Hallmark of Opiate Withdrawal
2001/12/01 by Andrew K Finn, Jennifer L. Whistler, Jennifer L Whistler · 286 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biology #Cell biology #Chemistry #DAMGO #Desensitization (medicine) #Endocytosis #Internal medicine #Medicine #Morphine #Neuropeptides and Animal Physiology #Neuroscience #Opiate #Opioid #Opioid receptor #Pharmacological Receptor Mechanisms and Effects #Pharmacology #Receptor #Receptor Mechanisms and Signaling #Receptor-mediated endocytosis #μ-opioid receptor
- Morphine‐like substance in leech ganglia
2000/04/01 by Virginie Laurent, Béatrice Salzet, Martine Verger‐Bocquet +2 · 18 citations
Chemistry · Medicine · Neuroscience · Psychology · #Biochemistry #Biology #Chemistry #Endocrinology #Leech #Lipopolysaccharide #Morphine #Neuroendocrine regulation and behavior #Nitric oxide #Pain Mechanisms and Treatments #Pharmacology #Receptor #Stress Responses and Cortisol
- Genetic Determinants of Severity of Acute Withdrawal From Diazepam in Mice
1999/07/01 by Pamela Metten, John C Crabbe, John C. Crabbe · 22 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Analysis of variance #Benzodiazepine #Biochemistry #Biology #Cross-tolerance #Diazepam #Drug #Ethanol #GABA and Rice Research #Gene #Genetic Mapping and Diversity in Plants and Animals #Genetics #Hypnotic #Inbred strain #Internal medicine #Medicine #Morphine #Neuroscience and Neuropharmacology Research #Pentobarbital #Pharmacology #Physical dependence #Receptor
- Comparison of analgesic efficacy of oxycodone and morphine in postoperative intravenous patient‐controlled analgesia
1998/05/01 by M. Silvasti, Per H. Rosenberg, Toni T. Seppälä +2 · 159 citations
Medicine · #Pain Management and Opioid Use #Anesthesia and Pain Management #Opioid Use Disorder Treatment #Medicine #Oxycodone #Morphine #Anesthesia #Analgesic #Vomiting #Nausea #Bolus (digestion) #Opioid #Visual analogue scale #Surgery #Internal medicine
- Formal Total Synthesis of (—)‐Morphine by Cuprate Conjugate Addition
1996/12/01 by Johann Mulzer, Gerd Dürner, Dirk Trauner · 58 citations
Chemistry · Mathematics · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Alkaloids: synthesis and pharmacology #Anesthesia #Chemical synthesis and alkaloids #Chemistry #Chromatography in Natural Products #Conjugate #Cuprate #Enone #Materials science #Mathematics #Medicine #Morphine #Stereochemistry #Steric effects #Total synthesis
- Asymmetric synthesis of either enantiomer of opium alkaloids and morphinans. Total synthesis of (-)- and (+)-dihydrocodeinone and (-)- and (+)-morphine
1993/11/01 by Chang Yong Hong, Noriyuki Kado, Larry E. Overman · 194 citations
Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Alkaloids: synthesis and pharmacology #Altmetrics #Berberine and alkaloids research #Bibliometrics #Chemical synthesis and alkaloids #Chemistry #Citation #Computer science #Enantiomer #History #Icon #Information retrieval #Informetrics #Medicine #Morphine #Opium #Pharmacology #Stereochemistry #World Wide Web
- Pharmacokinetics and Pharmacodynamics of Intranasal "Snorted" Heroin
1993/10/01 by Edward J. Cone, Barbara A Holicky, Therese M. Grant +2 · 91 citations
Pharmacology, Toxicology and Pharmaceutics · Medicine · #Forensic Toxicology and Drug Analysis #Cannabis and Cannabinoid Research #Opioid Use Disorder Treatment #Nasal administration #Heroin #Pharmacokinetics #Pharmacology #Medicine #Route of administration #Pharmacodynamics #Morphine #Placebo #Anesthesia #Drug
- The history and development of the fentanyl series
1992/04/01 by Theodore H. Stanley · 159 citations
Medicine · Veterinary · #Alfentanil #Anesthesia #Anesthesia and Pain Management #Anesthesia and Sedative Agents #Anesthetic #Blood pressure #Fentanyl #Internal medicine #Medicine #Morphine #Narcotic #Opioid #Sufentanil #Veterinary Pharmacology and Anesthesia
- Studies directed towards the total synthesis of morphine alkaloids
1982/01/01 by David A. Evans, D.A. Evans, C.H. Mitch +1 · 83 citations
Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Advanced Synthetic Organic Chemistry #Alkaloid #Alkaloids: synthesis and pharmacology #Chemical synthesis and alkaloids #Chemistry #Morphine #Pharmacology #Stereochemistry #Total synthesis