- Blunted Cardiac Mitophagy in Response to Metabolic Stress Contributes to HFpEF
2024/09/27 by Akira Yoshii, Timothy S. McMillen, Yajun Wang +9 · 27 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Autophagy #Beta oxidation #Biochemistry #Cardiac Fibrosis and Remodeling #Cardiology #Cardiovascular Function and Risk Factors #Chemistry #Ejection fraction #Endocrinology #Energy metabolism #Heart failure #Heart failure with preserved ejection fraction #Internal medicine #Medicine #Metabolism #Mitochondrial Function and Pathology #Mitochondrial ROS #Mitochondrion #Mitophagy #Oxidative stress #Phosphocreatine
- Mitochondrial fatty acid oxidation is the major source of cardiac adenosine triphosphate production in heart failure with preserved ejection fraction
2024/01/09 by Qiuyu Sun, Berna Güven, Cory S Wagg +20 · 26 citations
Chemistry · Medicine · #Adenosine triphosphate #Beta oxidation #Biochemistry #Cardiac Valve Diseases and Treatments #Cardiology #Cardiovascular Function and Risk Factors #Chemistry #Ejection fraction #Fatty acid #Heart Failure Treatment and Management #Heart failure #Internal medicine #Medicine #Mitochondrion
- Cardiac Energy Metabolism in Heart Failure
2021/05/13 by Gary D. Lopaschuk, Qutuba G. Karwi, Rong Tian +2 · 47 citations
Medicine · #Beta oxidation #Cardiac Fibrosis and Remodeling #Cardiac Ischemia and Reperfusion #Cardiovascular Function and Risk Factors #Glycolysis #Heart failure #Ketone bodies #Metabolism #Mitochondrion #NAD+ kinase #Oxidative phosphorylation #Oxidative stress
- Butyrate Regulates Liver Mitochondrial Function, Efficiency, and Dynamics in Insulin-Resistant Obese Mice
2017/02/21 by Maria Pina Mollica, Giuseppina Mattace Raso, Gina Cavaliere +14 · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #AMPK #Adipose Tissue and Metabolism #Beta oxidation #Biochemistry #Biology #Butyrate #Diet and metabolism studies #Endocrinology #Enzyme #Fatty liver #Fermentation #Insulin #Insulin resistance #Internal medicine #Medicine #Metabolism #Metabolomics and Mass Spectrometry Studies #Mitochondrion #Oxidative stress
- Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion
2016/09/30 by Yong Seon Choi, Ana Barbosa Marcondes de Mattos, Dan Shao +6 · 28 citations
Chemistry · Medicine · #Angiotensin II #Beta oxidation #Biochemistry #Blood pressure #Cardiac Fibrosis and Remodeling #Cardiology #Cardiovascular Disease and Adiposity #Cardiovascular Function and Risk Factors #Chemistry #Diastole #Endocrinology #Fatty acid #Internal medicine #Medicine
- Glucose metabolism and cardiac hypertrophy
2011/04/18 by Stephen C. Kolwicz, S. C. Kolwicz, R. Tian +1 · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #AMP-activated protein kinase #AMPK #Beta oxidation #Biochemistry #Biology #Carbohydrate metabolism #Cardiovascular Function and Risk Factors #Citric acid cycle #Endocrinology #Glucose uptake #Glycolysis #Insulin #Internal medicine #Kinase #Medicine #Metabolism #Metabolism, Diabetes, and Cancer #Mitochondrial Function and Pathology #Oxidative phosphorylation #Pentose phosphate pathway #Protein kinase A
- Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport
2010/09/13 by Yuki Kawano, Shin Nishiumi, Shinwa Tanaka +8 · 20 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Aryl #Aryl hydrocarbon receptor #Beta oxidation #Biochemistry #Chemistry #Diet and metabolism studies #Downregulation and upregulation #Fatty acid #Gene #Hydrocarbon #Internal medicine #Liver Disease Diagnosis and Treatment #Medicine #Metabolism and Genetic Disorders #Organic chemistry #Receptor #Steatosis
- A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic Steatosis
2010/03/18 by Jung Hoon Lee, Taira Wada, Maria Febbraio +5 · 30 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Environmental Science · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Aryl hydrocarbon receptor #Aryl hydrocarbon receptor nuclear translocator #Beta oxidation #Biochemistry #Biology #CD36 #Chemistry #Endocrinology #Fatty acid #Fatty liver #Gene #Internal medicine #Medicine #Peroxisome Proliferator-Activated Receptors #Pharmacogenetics and Drug Metabolism #Receptor #Steatosis #Toxic Organic Pollutants Impact #Transcription factor #adipocyte protein 2
- Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle
2006/01/25 by Jeanette Kuhl, Neil B. Ruderman, Nicolas Musi +14 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #AMP-activated protein kinase #AMPK #Adipose Tissue and Metabolism #Beta oxidation #Biochemistry #Chemistry #Coactivator #Endocrinology #Enzyme #Gene #Internal medicine #Malonyl-CoA #Medicine #Metabolism #Metabolism, Diabetes, and Cancer #Peroxisome Proliferator-Activated Receptors #Phosphorylation #Protein kinase A #Pyruvate carboxylase #Transcription factor
- Pancreatic Islet Adaptation to Fasting Is Dependent on Peroxisome Proliferator-Activated Receptor α Transcriptional Up-Regulation of Fatty Acid Oxidation
2004/12/15 by Sandrine Gremlich, Christopher J. Nolan, Christopher Nolan +13 · 23 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Adipose Tissue and Metabolism #Beta oxidation #Biochemistry #Biology #Carbohydrate metabolism #Endocrinology #Insulin #Internal medicine #Islet #Medicine #Metabolism #Nuclear receptor #Pancreatic function and diabetes #Peroxisome #Peroxisome Proliferator-Activated Receptors #Peroxisome proliferator-activated receptor #Peroxisome proliferator-activated receptor alpha #Receptor #Transcription factor
- Effects of l‐carnitine on the pyruvate dehydrogenase complex and carnitine palmitoyl transferase activities in muscle of endurance athletes
1994/03/14 by Joaquı́n Arenas, Joaquín Arenas, Rosa Huertas +4 · 11 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Athletes #Beta oxidation #Biochemistry #Carnitine #Carnitine O-palmitoyltransferase #Chemistry #Diet and metabolism studies #Endocrinology #Enzyme #Internal medicine #Medicine #Metabolism #Metabolism and Genetic Disorders #Mitochondrial Function and Pathology #Physical therapy #Placebo #Pyruvate dehydrogenase complex #Transferase