Lance Stewart
- Structures of Three Classes of Anticancer Agents Bound to the Human Topoisomerase I−DNA Covalent Complex
2005/02/24 by Bart L. Staker, M.D. Feese, Mark Cushman +4 · 18 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer therapeutics and mechanisms #Antibiotics Pharmacokinetics and Efficacy #Lung Cancer Research Studies
- Abundancia relativa y distribución de aves marinas frente a la costa peruana y su relación con la anchoveta. Crucero BIC Humboldt 9803-05 de Tumbes a Tacna
1998/07/01 by Aaron Chevalier, Daniel‐Adriano Silva, Gabriel J. Rocklin +28 · 1 voice · 8 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Social Sciences · #Geography and Environmental Studies in Latin America #Monoclonal and Polyclonal Antibodies Research #Protein Structure and Dynamics #RNA and protein synthesis mechanisms
- Synthesis and Mechanism of Action Studies of a Series of Norindenoisoquinoline Topoisomerase I Poisons Reveal an Inhibitor with a Flipped Orientation in the Ternary DNA−Enzyme−Inhibitor Complex As Determined by X-ray Crystallographic Analysis
2005/06/23 by Alexandra Ioanoviciu, Smitha Antony, Yves Pommier +3 · 12 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Cancer therapeutics and mechanisms #Synthesis and biological activity #Bioactive Compounds and Antitumor Agents
- A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex
2006/02/01 by Christophe Marchand, Smitha Antony, Kurt W. Kohn +6 · 5 citations
Biochemistry, Genetics and Molecular Biology · Pharmacology, Toxicology and Pharmaceutics · Medicine · #Cancer therapeutics and mechanisms #Bioactive Compounds and Antitumor Agents #Neutropenia and Cancer Infections
- Whole Gene Synthesis: A Gene-O-Matic Future
2005/01/01 by Lance Stewart, Alex B. Burgin · 2 citations
Biochemistry, Genetics and Molecular Biology · #Genetics, Bioinformatics, and Biomedical Research
- An artificial intelligence accelerated virtual screening platform for drug discovery
2024/09/05 by Guangfeng Zhou, Domnița-Valeria Rusnac, Hahnbeom Park +9 · 1 voice · 5 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · Materials Science · #Computational Drug Discovery Methods #Machine Learning in Materials Science #Protein Structure and Dynamics
- De novo designed proteins neutralize lethal snake venom toxins
2025/01/15 by Susana Vázquez Torres, Melisa Bénard-Valle, Stephen P. Mackessy +30 · 2 voices · 4 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Venomous Animal Envenomation and Studies #Rabies epidemiology and control #Biochemical and Structural Characterization