- Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver
2020/12/16 by Sunmi Seok, Hao Sun, Young-Chae Kim +3 · 15 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biochemistry #Cancer research #Chemistry #Disease #Endocrinology #Farnesoid X receptor #Fatty liver #Insulin #Insulin resistance #Internal medicine #Medicine #MicroRNA in disease regulation #Nonalcoholic fatty liver disease #Nuclear Receptors and Signaling #Nuclear receptor #Obeticholic acid #Peroxisome proliferator-activated receptor #RNA Research and Splicing #Receptor #Small heterodimer partner #Transactivation #Transcription factor
- Conserved miR164-targeted NAC genes negatively regulate drought resistance in rice
2014/03/06 by Yujie Fang, Kabin Xie, Lizhong Xiong · 28 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Arabidopsis #Biology #Conserved sequence #Gene #Gene expression #Genetics #Mutant #Peptide sequence #Photosynthetic Processes and Mechanisms #Plant Molecular Biology Research #Plant Stress Responses and Tolerance #Transactivation #microRNA
- Dynamic Transition States of ErbB1 Phosphorylation Predicted by Spatial Stochastic Modeling
2013/09/01 by Meghan McCabe Pryor, Meghan McCabe Pryor, Shalini T. Low-Nam +9 · 5 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Biophysics #Chemistry #Dimer #Glycosylation and Glycoproteins Research #HER2/EGFR in Cancer Research #Monoclonal and Polyclonal Antibodies Research #Monomer #Phosphorylation #Stereochemistry #Transactivation
- Coronin 2A mediates actin-dependent de-repression of inflammatory response genes
2011/02/01 by Wendy Huang, Serena Ghisletti, Kaoru Saijo +10 · 1 citation
Immunology and Microbiology · Medicine · #Biology #Cell biology #Corepressor #Gene #Gene expression #Genetics #Immune Response and Inflammation #Inflammatory mediators and NSAID effects #Nuclear receptor #Phosphorylation #Psychological repression #SUMO protein #Transactivation #Transcription factor #Transrepression #interferon and immune responses
- Nuclear Translocation of β-Actin Is Involved in Transcriptional Regulation during Macrophage Differentiation of HL-60 Cells
2010/01/07 by Yong Xu, Thusanth Thuraisingam, David Anderson de Lima Morais +2 · 2 citations
Biochemistry, Genetics and Molecular Biology · #Cellular Mechanics and Interactions #RNA Research and Splicing #Molecular Biology Techniques and Applications #Biology #Cell biology #Chromatin immunoprecipitation #Transactivation #Actin #Molecular biology #Gene knockdown #Cell nucleus #Gene expression #Signal transduction #Regulation of gene expression #Gene #Cytoplasm #Promoter #Genetics
- Functional evidence implicating FOXL2 in non-syndromic premature ovarian failure and in the regulation of the transcription factor OSR2
2009/05/07 by P Laissue, Paul Laissue, B Lakhal +19 · 16 citations
Biochemistry, Genetics and Molecular Biology · #Biology #Blepharophimosis #Congenital heart defects research #Endocrinology #Forkhead Transcription Factors #Gene #Genetic Syndromes and Imprinting #Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities #Genetics #Premature ovarian failure #Ptosis #Transactivation #Transcription factor
- Nuclear actin and actin‐binding proteins in the regulation of transcription and gene expression
2009/03/23 by Bin Zheng, Mei Han, Michel Bernier +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #Cellular Mechanics and Interactions #Muscle Physiology and Disorders #Cell biology #Actin-binding protein #Biology #MDia1 #Actin remodeling #Transcription factor #Transactivation #Actin #Actin cytoskeleton #Gene #Biochemistry #Cytoskeleton #Cell
- Identification of a Novel Family of Ankyrin Repeats Containing Cofactors for p160 Nuclear Receptor Coactivators
2004/06/08 by Aihua Zhang, Percy Luk Yeung, Chia‐Wei Li +6 · 26 citations
Biochemistry, Genetics and Molecular Biology · #Ankyrin #Ankyrin repeat #Biology #Cell biology #Epigenetics and DNA Methylation #Gene #Genetics #Genomics and Chromatin Dynamics #Molecular biology #Nuclear receptor #Nuclear receptor coactivator 1 #Nuclear receptor coactivator 2 #Receptor Mechanisms and Signaling #Transactivation #Transcription factor
- Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation
2003/08/01 by Clifford D. Mol, Kheng B. Lim, Vandana Sridhar +9 · 29 citations
Chemistry · Immunology and Microbiology · Medicine · #Biochemistry #Biology #Cancer research #Cell biology #Chemistry #Chronic Myeloid Leukemia Treatments #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Haematopoiesis #Mast cells and histamine #Proto-Oncogene Proteins c-kit #Proto-oncogene tyrosine-protein kinase Src #Receptor tyrosine kinase #Signal transduction #Stem cell #Stem cell factor #Transactivation #Transcription factor #Tyrosine kinase
- Two Initiator-like Elements Are Required for the Combined Activation of the Human Apolipoprotein C-III Promoter by Upstream Stimulatory Factor and Hepatic Nuclear Factor-4
2002/04/01 by D. Pastier, Jean‐Marc Lacorte, Jean Chambaz +2 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · #Retinoids in leukemia and cellular processes #Signaling Pathways in Disease #Protein Kinase Regulation and GTPase Signaling #Transactivation #Transcription factor #Molecular biology #Binding site #Response element #Footprinting #Transfection #Promoter #Chemistry #Mutation #Biology #Gene #Biochemistry #Gene expression
- Biological and clinical associations of c-jun activation in human breast cancer
2000/03/20 by Julia M.W. Gee, Julia M. W. Gee, A. Filipa Barroso +5 · 23 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Breast cancer #Cancer #Cancer research #Cell biology #Endocrinology #Estrogen and related hormone effects #Gene #HER2/EGFR in Cancer Research #Internal medicine #Kinase #MAPK/ERK pathway #Medicine #Metastasis #Transactivation #Transcription factor #Ubiquitin and proteasome pathways #c-jun
- Determinants of Specificity of Transactivation by the Mineralocorticoid or Glucocorticoid Receptor*
1997/06/01 by Sylvia S. Lim-Tio, Maria-Cristina Keightley, Peter J. Fuller · 4 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Aldosterone #Biochemistry #Biology #Cardiovascular, Neuropeptides, and Oxidative Stress Research #Cell biology #Cell culture #Context (archaeology) #Endocrinology #Estrogen and related hormone effects #Gene #Genetics #Glucocorticoid #Glucocorticoid receptor #Hormonal Regulation and Hypertension #In vivo #Internal medicine #Medicine #Mineralocorticoid #Mineralocorticoid receptor #Nuclear receptor #Nuclear receptor coactivator 2 #Receptor #Transactivation #Transcription factor
- The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11 beta-hydroxysteroid dehydrogenase.
1994/09/01 by Marc Lombès, M Lombes, S Kenouch +7 · 16 citations
Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Adrenal Hormones and Disorders #Aldosterone #Biochemistry #Biology #Carbenoxolone #Chemistry #Corticosterone #Dehydrogenase #Endocrinology #Enzyme #Gene #Gene expression #Hormonal Regulation and Hypertension #Hormone #Internal medicine #Intracellular #Medicine #Mineralocorticoid #Mineralocorticoid receptor #Pharmacogenetics and Drug Metabolism #Receptor #Transactivation