1. Alterations in Adipose Tissue Distribution, Cell Morphology, and Function Mark Primary Insulin Hypersecretion in Youth With Obesity
   2023/10/23 by Domenico Tricò, Martina Chiriacò, Jessica Nouws +11 · 15 citations
   Medicine · #Abdominal obesity #Adipocyte #Adipokines, Inflammation, and Metabolic Diseases #Adipose Tissue and Metabolism #Adipose tissue #Biology #Diabetes, Cardiovascular Risks, and Lipoproteins #Endocrinology #Glucose uptake #Hyperinsulinemia #Insulin #Insulin resistance #Internal medicine #Leptin #Medicine #Metabolic syndrome #Obesity
2. NLRP3 at the crossroads between immune/inflammatory responses and enteric neuroplastic remodelling in a mouse model of diet‐induced obesity
   2021/05/17 by Carolina Pellegrini, Matteo Fornai, Laura Benvenuti +20 · 8 citations
   Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Adipokine #Diet-induced obese #Endocrinology #Gastrointestinal motility and disorders #IL-33, ST2, and ILC Pathways #Immune system #Immunology #Inflammasome #Inflammasome and immune disorders #Inflammation #Insulin resistance #Internal medicine #Leptin #Medicine #Obesity #Resistin
3. Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression
   2019/11/01 by Shelly Nason, Shelly R Nason, Teayoun Kim +9 · 10 citations
   Medicine · Neuroscience · Nursing · #Agonist #Biochemical Analysis and Sensing Techniques #Biology #Endocrinology #Fatty liver #Glucagon #Glucagon receptor #Glucagon-like peptide 1 receptor #Insulin #Internal medicine #Leptin #Leptin receptor #Medicine #Obesity #Pancreatic function and diabetes #Receptor #Regulation of Appetite and Obesity #Steatosis
4. Obesity and Insulin Resistance Are Inversely Associated with Serum and Adipose Tissue Carotenoid Concentrations in Adults
   2019/07/16 by Ayelet Harari, Adelle CF Coster, Adelle C.F. Coster +9 · 26 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Adipokines, Inflammation, and Metabolic Diseases #Adipose tissue #Antioxidant Activity and Oxidative Stress #Biochemistry #Biology #Carotenoid #Chemistry #Endocrinology #Insulin #Insulin resistance #Internal medicine #Leptin #Lutein #Medicine #Obesity #Retinoids in leukemia and cellular processes #White adipose tissue
5. Effects of SCFA on the DNA methylation pattern of adiponectin and resistin in high-fat-diet-induced obese male mice
   2018/06/21 by Yuanyuan Lu, Chaonan Fan, Aimin Liang +4 · 26 citations
   Chemistry · Medicine · Neuroscience · #Adipokine #Adipokines, Inflammation, and Metabolic Diseases #Adiponectin #Adipose Tissue and Metabolism #Adipose tissue #Biochemistry #Biology #Butyrate #Chemistry #DNA methylation #DNA methyltransferase #Endocrinology #Gene #Gene expression #Insulin resistance #Internal medicine #Leptin #Medicine #Obesity #Regulation of Appetite and Obesity #Resistin
6. Adipokines as emerging depression biomarkers: A systematic review and meta-analysis
   2014/08/19 by André F. Carvalho, Davi Q.C. Rocha, Roger S. McIntyre +9 · 26 citations
   Medicine · Neuroscience · Psychology · #Adipokine #Adipokines, Inflammation, and Metabolic Diseases #Adiponectin #Adipose Tissue and Metabolism #Antidepressant #Confounding #Depression (economics) #Endocrinology #Internal medicine #Leptin #Major depressive disorder #Medicine #Meta-analysis #Obesity #Psychology #Regulation of Appetite and Obesity #Resistin
7. Metabolic regulation by protein tyrosine phosphatases
   2014/01/01 by Hilla Knobler, Ari Elson · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cancer, Hypoxia, and Metabolism #Cell biology #Endocrinology #Insulin #Insulin receptor #Insulin resistance #Internal medicine #Leptin #Leptin receptor #Medicine #Metabolic syndrome #Metabolism, Diabetes, and Cancer #Obesity #Phosphorylation #Protein Tyrosine Phosphatases #Protein tyrosine phosphatase #Receptor #Signal transduction #Tyrosine #Tyrosine phosphorylation
8. The Role of “Mixed” Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Relevance to Food Intake and Nutritional Status in Patients with Anorexia Nervosa and Bulimia Nervosa
   2013/01/01 by Kvido Smitka, Hana Papežová, K Vondra +3 · 1 citation
   Psychology · Neuroscience · Nursing · Medicine · #Eating Disorders and Behaviors #Regulation of Appetite and Obesity #Biochemical Analysis and Sensing Techniques #Orexigenic #Ghrelin #Endocrinology #Internal medicine #Peptide YY #Medicine #Neuropeptide Y receptor #Leptin #Appetite #Neuropeptide #Hypothalamus #Hormone #Obesity
9. Long-term fasting in the anadromous Arctic charr is associated with down-regulation of metabolic enzyme activity and up-regulation of leptin A1 and SOCS expression in the liver.
   2013/01/01 by Even H. Jørgensen, Mads Martinsen, Vidar Strøm +5 · 10 citations
   Agricultural and Biological Sciences · Environmental Science · Immunology and Microbiology · Medicine · #Aquaculture Nutrition and Growth #Aquaculture disease management and microbiota #Biochemistry #Biology #Ecology #Endocrinology #Fish migration #Fishery #Gene #Internal medicine #Leptin #Medicine #Obesity #Physiological and biochemical adaptations #SOCS3 #Salvelinus #Trout
10. An ex vivo co‐culture model system to evaluate stromal–epithelial interactions in breast cancer
    2012/06/14 by Therese S. Salameh, T.S. Salameh, T.T. Le +9 · 13 citations
    Medicine · #Adipokine #Adipose tissue #Biology #Body Contouring and Surgery #Breast cancer #Cancer #Cancer Cells and Metastasis #Cancer research #Carcinogenesis #Endocrinology #Internal medicine #Leptin #Mammary gland #Mammary tumor #Medicine #Mesenchymal stem cell research #Pathology #Stromal cell #Tumor microenvironment #Tumor progression
11. CRF treatment induces a readjustment in glucosensing capacity in the hypothalamus and hindbrain of rainbow trout
    2011/10/26 by Marta Conde-Sieira, Marta Conde‐Sieira, Marta Librán-Pérez +4 · 7 citations
    Chemistry · Medicine · Neuroscience · #Adipose Tissue and Metabolism #Biology #Cart #Central nervous system #Chemistry #Endocrinology #Forebrain #Glucokinase #Glycogen #Hindbrain #Hypothalamus #Insulin #Internal medicine #Leptin #Medicine #Neuropeptide #Neuropeptide Y receptor #Obesity #Orexin #Receptor #Regulation of Appetite and Obesity #Stress Responses and Cortisol
12. Piperidine alkaloids from Piper retrofractum Vahl. protect against high-fat diet-induced obesity by regulating lipid metabolism and activating AMP-activated protein kinase
    2011/07/01 by Kyung Jin Kim, Myoung-Su Lee, Keunae Jo +2 · 24 citations
    Chemistry · Medicine · Nursing · Pharmacology, Toxicology and Pharmaceutics · #AMP-activated protein kinase #AMPK #Adipocyte #Adipose tissue #Biochemical Analysis and Sensing Techniques #Biochemistry #Biology #Chemistry #Cholesterol #Endocrinology #Ginger and Zingiberaceae research #Internal medicine #Kinase #Leptin #Lipid metabolism #Medicine #Obesity #Peroxisome proliferator-activated receptor #Pharmacology #Piperaceae Chemical and Biological Studies #Piperine #Protein kinase A #Receptor #Triglyceride
13. Perivascular adipose tissue as a cause of atherosclerosis
    2010/06/02 by Sandra N. Verhagen, Frank L.J. Visseren · 27 citations
    Medicine · #Adipokine #Adipose tissue #Artery #Biology #Cardiology #Cardiovascular Disease and Adiposity #Cardiovascular, Neuropeptides, and Oxidative Stress Research #Coronary arteries #Coronary artery disease #Coronary atherosclerosis #Ex vivo #In vivo #Inflammation #Internal medicine #Leptin #Medicine #Obesity #Pathology
14. The Effect of Periodontal Treatment on Serum Leptin, Interleukin‐6, and C‐Reactive Protein
    2010/04/07 by Yasuko Shimada, Yasutaka Komatsu, Ikuyo Ikezawa‐Suzuki +3 · 26 citations
    Dentistry · Medicine · Neuroscience · #Adiponectin #Adipose tissue #Body mass index #C-reactive protein #Chronic periodontitis #Clinical attachment loss #Cytokine #Endocrinology #Inflammation #Insulin resistance #Interleukin #Interleukin 6 #Internal medicine #Leptin #Medicine #Obesity #Oral microbiology and periodontitis research #Periodontitis #Regulation of Appetite and Obesity #Salivary Gland Disorders and Functions
15. Adverse metabolic and cardiovascular consequences of circadian misalignment
    2009/03/02 by Frank A. J. L. Scheer, Michael F. Hilton, Christos S. Mantzoros +1 · 2 citations
    Neuroscience · Medicine · #Circadian rhythm and melatonin #Dietary Effects on Health #Thermoregulation and physiological responses #Circadian rhythm #Internal medicine #Endocrinology #Medicine #Blood pressure #Obesity #Shift work #Heart rate #Insulin #Diabetes mellitus #Postprandial #Leptin
16. Peripheral Administration of Nesfatin-1 Reduces Food Intake in Mice: The Leptin-Independent Mechanism
    2009/01/27 by Hiroyuki Shimizu, H. Shimizu, Sinsuke Oh-I +25 · 26 citations
    Chemistry · Medicine · Neuroscience · Nursing · #Adipokines, Inflammation, and Metabolic Diseases #Anorexia #Arcuate nucleus #Biochemical Analysis and Sensing Techniques #Biology #Chemistry #Cholinergic #Endocrinology #Hypothalamus #Internal medicine #Leptin #Medicine #Obesity #Proopiomelanocortin #Regulation of Appetite and Obesity #Solitary nucleus #Stimulation
17. Diurnal Variation of Human Sweet Taste Recognition Thresholds Is Correlated With Plasma Leptin Levels
    2008/07/16 by Yuki Nakamura, Keisuke Sanematsu, Rie Ohta +5 · 1 citation
    Nursing · Neuroscience · Chemistry · Medicine · #Biochemical Analysis and Sensing Techniques #Regulation of Appetite and Obesity #Olfactory and Sensory Function Studies #Leptin #Taste #Internal medicine #Endocrinology #Diurnal temperature variation #Circadian rhythm #Morning #Meal #Leptin receptor #Chemistry #Biology #Obesity #Medicine #Food science
18. Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?
    2008/04/09 by Paul Trayhurn, Bohan Wang, I. Stuart Wood · 28 citations
    Chemistry · Medicine · #Adipocyte #Adipokine #Adipokines, Inflammation, and Metabolic Diseases #Adiponectin #Adipose Tissue and Metabolism #Adipose tissue #Adipose tissue macrophages #Biology #Chemistry #Endocrinology #Hypoxia (environmental) #Inflammation #Insulin #Insulin resistance #Internal medicine #Leptin #Lipid metabolism and disorders #Medicine #Obesity #White adipose tissue
19. Selective Loss of Leptin Receptors in the Ventromedial Hypothalamic Nucleus Results in Increased Adiposity and a Metabolic Syndrome
    2008/02/07 by Nathan C. Bingham, Kimberly K. Anderson, Anne L. Reuter +2 · 26 citations
    Medicine · Neuroscience · #Adipokines, Inflammation, and Metabolic Diseases #Adipose Tissue and Metabolism #Adipose tissue #Arcuate nucleus #Biology #Endocrinology #Energy homeostasis #Glucose homeostasis #Hypothalamus #Insulin resistance #Internal medicine #Leptin #Leptin receptor #Medicine #Obesity #Regulation of Appetite and Obesity
20. Human epicardial adipose tissue: A review
    2007/05/30 by Harold S. Sacks, John N. Fain · 33 citations
    Medicine · #Adipokine #Adiponectin #Adipose tissue #Artery #Cardiology #Cardiovascular Disease and Adiposity #Cardiovascular, Neuropeptides, and Oxidative Stress Research #Coronary arteries #Coronary artery disease #Coronary atherosclerosis #Endocrinology #Epicardial fat #Inflammation #Insulin resistance #Internal medicine #Leptin #Medicine #Obesity #Proinflammatory cytokine
21. Increased Hypothalamic Protein Tyrosine Phosphatase 1B Contributes to Leptin Resistance with Age
    2006/10/13 by Christopher D. Morrison, Christy L. White, Zhong Wang +6 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · Nursing · #Biochemical Analysis and Sensing Techniques #Biology #Endocrinology #Food intake #Hypothalamus #Internal medicine #Leptin #Leptin receptor #Medicine #Obesity #Protein Tyrosine Phosphatases #Regulation of Appetite and Obesity
22. 2-Deoxyglucose as an Energy Restriction Mimetic Agent: Effects on Mammary Carcinogenesis and on Mammary Tumor Cell Growth In vitro
    2005/08/01 by Zongjian Zhu, Weiqin Jiang, John N. McGinley +1 · 27 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Adipose Tissue and Metabolism #Biochemistry #Biology #Breast cancer #Cancer #Carbohydrate metabolism #Carcinogenesis #Cell growth #Deoxyglucose #Dietary Effects on Health #Endocrinology #Glucose uptake #Insulin #Internal medicine #Leptin #Mammary tumor #Medicine #Metabolism, Diabetes, and Cancer #Obesity
23. Leptin in Immunology
    2005/03/01 by Giuseppe Matarese, Stergios Moschos, Christos S. Mantzoros +1 · 31 citations
    Medicine · Neuroscience · Nursing · #Adipokine #Adipokines, Inflammation, and Metabolic Diseases #Biochemical Analysis and Sensing Techniques #Biology #Cytokine #Endocrinology #Energy homeostasis #Homeostasis #Immune system #Immunology #Inflammation #Internal medicine #Leptin #Medicine #Obesity #Pathophysiology #Proinflammatory cytokine #Regulation of Appetite and Obesity
24. Adipose Tissue as an Endocrine Organ
    2004/06/01 by Erin E. Kershaw, Jeffrey S. Flier · 46 citations
    Medicine · Neuroscience · #Adipokine #Adipokines, Inflammation, and Metabolic Diseases #Adiponectin #Adipose Tissue and Metabolism #Adipose tissue #Adipose tissue macrophages #Biology #Connective tissue #Diabetes mellitus #Endocrine system #Endocrinology #Hormone #Insulin resistance #Internal medicine #Leptin #Medicine #Obesity #Regulation of Appetite and Obesity #Resistin #White adipose tissue
25. Caloric restriction reverses the deficits in leptin receptor protein and leptin signaling capacity associated with diet-induced obesity: role of leptin in the regulation of hypothalamic long-form leptin receptor expression
    2004/05/01 by J Wilsey, Jared Wilsey, PJ Scarpace · 27 citations
    Chemistry · Medicine · Neuroscience · Nursing · #Adipokine #Adipokines, Inflammation, and Metabolic Diseases #Appetite #Biochemical Analysis and Sensing Techniques #Biology #Cell biology #Chemistry #Diet-induced obese #Endocrinology #Hypothalamus #Insulin resistance #Internal medicine #Leptin #Leptin receptor #Medicine #Obesity #Phosphorylation #Receptor #Regulation of Appetite and Obesity #SOCS3 #STAT3
26. Leptin Signaling in the Hypothalamus during Chronic Central Leptin Infusion
    2003/06/04 by Rekha Pal, Abhiram Sahu · 16 citations
    Medicine · Neuroscience · Nursing · #Adipokines, Inflammation, and Metabolic Diseases #Biochemical Analysis and Sensing Techniques #Biology #Cell biology #Endocrinology #Hypothalamus #Internal medicine #Leptin #Leptin receptor #Medicine #Obesity #Phosphorylation #Receptor #Regulation of Appetite and Obesity #SOCS3 #STAT protein #STAT3 #Signal transduction
27. Daily patterns of plasma leptin in sheep: effects of photoperiod and food intake
    2001/07/01 by M Marie, M. Marie, PA Findlay +4 · 18 citations
    Chemistry · Medicine · Neuroscience · Nursing · #Adipokines, Inflammation, and Metabolic Diseases #Animal science #Biochemical Analysis and Sensing Techniques #Biology #Blood plasma #Blood sampling #Chemistry #Circadian rhythm #Darkness #Endocrinology #Food intake #Insulin #Internal medicine #Leptin #Meal #Medicine #NEFA #Obesity #Regulation of Appetite and Obesity #photoperiodism
28. Apolipoprotein D interacts with the long form leptin receptor: a hypothalamic function in the control of energy homeostasis
    2001/02/26 by Zhitong Liu, Guo‐Qing Chang, Sarah F. Leibowitz · 2 citations
    Neuroscience · Medicine · Chemistry · #Regulation of Appetite and Obesity #Adipokines, Inflammation, and Metabolic Diseases #Circadian rhythm and melatonin #Internal medicine #Endocrinology #Leptin #Leptin receptor #Hypothalamus #Energy homeostasis #Apolipoprotein B #Receptor #Homeostasis #Biology #Chemistry #Obesity #Medicine #Cholesterol
29. Leptin in Pregnancy
    2000/11/01 by Michael C. Henson, V. Daniel Castracane · 25 citations
    Medicine · Neuroscience · #Adipokine #Adipokines, Inflammation, and Metabolic Diseases #Adipose Tissue and Metabolism #Adipose tissue #Autocrine signalling #Biology #Conceptus #Endocrinology #Fetus #Hormone #Internal medicine #Leptin #Leptin receptor #Medicine #Obesity #Paracrine signalling #Placenta #Placental insufficiency #Pregnancy #Receptor #Regulation of Appetite and Obesity #Syncytiotrophoblast
30. Hypertension in Obesity and the Leptin Receptor Gene Locus1
    2000/09/01 by Roland Rosmond, Yvon C. Chagnon, Göran Holm +7 · 9 citations
    Chemistry · Medicine · Neuroscience · #Adipokines, Inflammation, and Metabolic Diseases #Biology #Chemistry #Endocrinology #Gene #Genetics #Internal medicine #Leptin #Locus (genetics) #Medicine #Obesity #Receptor #Regulation of Appetite and Obesity

more