- Cannabidiol is a negative allosteric modulator of the cannabinoid CB 1 receptor
2015/07/27 by Robert B. Laprairie, R B Laprairie, A M Bagher +5 · 35 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Agonist #Allosteric modulator #Allosteric regulation #Biochemistry #Biology #Cannabidiol #Cannabinoid #Cannabinoid receptor #Cannabinoid receptor type 2 #Cannabis #Cannabis and Cannabinoid Research #Chemistry #Functional selectivity #Medicine #Neuroscience of respiration and sleep #Pharmacological Receptor Mechanisms and Effects #Pharmacology #Receptor
- Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006/06/28 by Jonathan D. Urban, William P. Clarke, Mark von Zastrow +11 · 45 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · Pharmacology, Toxicology and Pharmaceutics · #Agonist #Biochemistry #Biology #Cell biology #Chemistry #Computational biology #Functional selectivity #G protein-coupled receptor #Intrinsic activity #Mechanism (biology) #Molecular Pharmacology #Neuropeptides and Animal Physiology #Neuroscience #Partial agonist #Pharmacogenetics and Drug Metabolism #Pharmacology #Receptor #Receptor Mechanisms and Signaling #Signal transduction