Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

2001/01/01 by Mary E. Brunkow, Eric W. Jeffery, Kathryn A. Hjerrild +9 · 15 citations
Immunology and Microbiology · Nursing · #Aquaculture disease management and microbiota #Invertebrate Immune Response Mechanisms #Vitamin C and Antioxidants Research

paper · doi:10.1038/83784

crossref issued 2001/01/01 · crossref published 2001/01/01 · crossref published-print 2001/01/01 · openalex publication_date 2001/01/01 · crossref created 2002/07/26 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04 · crossref indexed 2026/08/05

Citations

• The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
• X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
• Analysis of hepatocyte nuclear factor-3β protein domains required for transcriptional activation and nuclear targeting
• Basic local alignment search tool

Cited by

• Control of Regulatory T Cell Development by the Transcription Factor Foxp3
• Foxp3 occupancy and regulation of key target genes during T-cell stimulation
• FOXP3 ensembles in T‐cell regulation
• Scurfin (FOXP3) Acts as a Repressor of Transcription and Regulates T Cell Activation
• IPEX as a Result of Mutations in FOXP3
• Mutational Analysis of the FOXP3 Gene and Evidence for Genetic Heterogeneity in the Immunodysregulation, Polyendocrinopathy, Enteropathy Syndrome
• A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice
• X-chromosome inactivation analysis in a female carrier of FOXP3 mutation
• Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3
• FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT
• The regulation of Foxp3 expression in regulatory CD4+CD25+T cells: Multiple pathways on the road
• A functional polymorphism in the promoter/enhancer region of the FOXP3/Scurfin gene associated with type 1 diabetes
• GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large
• The Human T Cell Response to Melanoma Antigens
• FOXP3 [wikipedia]