Foxp3 occupancy and regulation of key target genes during T-cell stimulation

2007/01/21 by Alexander Marson, Karsten Kretschmer, Garrett M. Frampton +8 · 1 citation
Immunology and Microbiology · #Immune Cell Function and Interaction #Immunotherapy and Immune Responses #T-cell and B-cell Immunology

paper · doi:10.1038/nature05478

crossref issued 2007/01/21 · crossref published 2007/01/21 · crossref published-online 2007/01/21 · openalex publication_date 2007/01/21 · crossref created 2007/01/21 · crossref published-print 2007/02/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · crossref indexed 2026/07/15 · openalex updated_date 2026/08/01

Citations

• The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
• X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
• Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
• Control of Regulatory T Cell Development by the Transcription Factor Foxp3
• Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Cited by

• FOXP3 [wikipedia]