Michael J. Pikal

1. Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix?
   2005/05/26 by Liuquan Chang, Liuquan (Lucy) Chang, Deanna Shepherd +6 · 31 citations
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Microencapsulation and Drying Processes #Protein purification and stability #Proteins in Food Systems
2. Lyophilized Drug Product Cake Appearance: What Is Acceptable?
   2017/03/22 by Sajal Manubhai Patel, Sajal M. Patel, Steven L. Nail +6 · 25 citations
   Biochemistry, Genetics and Molecular Biology · Materials Science · Agricultural and Biological Sciences · #Protein purification and stability #Crystallization and Solubility Studies #Microencapsulation and Drying Processes
3. Impact of sucrose level on storage stability of proteins in freeze-dried solids: I. correlation of protein–sugar interaction with native structure preservation
   2008/12/10 by Bingquan Wang, Serguei Tchessalov, Nicholas W. Warne +1 · 14 citations
   Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Protein purification and stability #Proteins in Food Systems #Microbial Inactivation Methods