Nevan J. Krogan
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
2020/04/30 by David E. Gordon, Gwendolyn Μ. Jang, Gwendolyn M. Jang +144 · 51 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · Medicine · #Computational Drug Discovery Methods #SARS-CoV-2 and COVID-19 Research #vaccines and immunoinformatics approaches
- COMPASS, a Histone H3 (Lysine 4) Methyltransferase Required for Telomeric Silencing of Gene Expression
2002/03/01 by Nevan J. Krogan, Jim Dover, Shahram Khorrami +4 · 8 citations
Biochemistry, Genetics and Molecular Biology · #Genomics and Chromatin Dynamics #Cancer-related gene regulation #Epigenetics and DNA Methylation
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection
2020/06/28 by Mehdi Bouhaddou, Danish Memon, Bjoern Meyer +91 · 8 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Endoplasmic Reticulum Stress and Disease #SARS-CoV-2 and COVID-19 Research #interferon and immune responses
- The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation
2003/03/01 by Nevan J. Krogan, Jim Dover, Adam Wood +11 · 5 citations
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #Epigenetics and DNA Methylation #Genomics and Chromatin Dynamics
- How many human proteoforms are there?
2018/02/14 by Ruedi Aebersold, Jeffrey N. Agar, Jeffrey N Agar +87 · 4 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Proteomics Techniques and Applications #Bioinformatics and Genomic Networks #RNA and protein synthesis mechanisms
- Cotranscriptional Set2 Methylation of Histone H3 Lysine 36 Recruits a Repressive Rpd3 Complex
2005/11/01 by Michael‐Christopher Keogh, Michael-Christopher Keogh, Siavash K. Kurdistani +21 · 3 citations
Biochemistry, Genetics and Molecular Biology · #Fungal and yeast genetics research #Genomics and Chromatin Dynamics #RNA Research and Splicing
- Phenotypic Landscape of a Bacterial Cell
2010/12/24 by Robert J. Nichols, Saunak Sen, Śaunak Sen +16 · 2 citations
Biochemistry, Genetics and Molecular Biology · #Bacterial Genetics and Biotechnology #Evolution and Genetic Dynamics #Genomics and Phylogenetic Studies
- De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking
2023/10/20 by Zhen Chen, Momoko Shiozaki, Kelsey M. Haas +10 · 1 voice · 4 citations
Biochemistry, Genetics and Molecular Biology · #Advanced Electron Microscopy Techniques and Applications #Molecular Biology Techniques and Applications #Renal and related cancers
- Large scale prospective evaluation of co-folding across 557 Mac1-ligand complexes and three virtual screens
2025/12/28 by Jongbin Kim, G.J. Correy, Brendan W. Hall +17 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Computer Science · #Computational Drug Discovery Methods #Pharmacological Receptor Mechanisms and Effects #Protein Structure and Dynamics
- A ciliopathy complex builds distal appendages to initiate ciliogenesis
2021/06/15 by Dhivya Kumar, Addison B. Rains, Addison Rains +15 · 23 citations
Biochemistry, Genetics and Molecular Biology · #Anatomy #Appendage #Biology #Cell #Cell biology #Cell cycle #Centriole #Centrosome #Ciliogenesis #Ciliopathies #Ciliopathy #Cilium #Genetic and Kidney Cyst Diseases #Genetics #Hedgehog Signaling Pathway Studies #Microtubule #Microtubule and mitosis dynamics
- Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection
2020/06/01 by Jessica Ho, Matthew Angel, Yixuan Ma +51 · 1 citation
Environmental Science · Medicine · Biochemistry, Genetics and Molecular Biology · #Bacteriophages and microbial interactions #Respiratory viral infections research #RNA and protein synthesis mechanisms