Dennis E. Discher
- Myotubes differentiate optimally on substrates with tissue-like stiffness
2004/09/13 by Adam J. Engler, Maureen A. Griffin, Shamik Sen +4 · 42 citations
Biochemistry, Genetics and Molecular Biology · Engineering · #3D Printing in Biomedical Research #Actin #Adhesion #Anatomy #Biology #Biophysics #Cell adhesion #Cell biology #Cellular Mechanics and Interactions #Composite material #Materials science #Muscle Physiology and Disorders #Myocyte #Myogenesis #Myosin #Sarcomere #Stiffness #Vinculin
- Inhibition of “self” engulfment through deactivation of myosin-II at the phagocytic synapse between human cells
2008/03/10 by Richard Tsai, Richard K. Tsai, Dennis E. Discher · 29 citations
Immunology and Microbiology · Medicine · #Actin #Biology #CD47 #Cell Adhesion Molecules Research #Cell biology #Erythrocyte Function and Pathophysiology #Immune system #Immunological synapse #Immunology #Myosin #Myosin light-chain kinase #Phagocytosis #Phagocytosis and Immune Regulation #Phagosome #T cell #T-cell receptor
- Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
2008/10/29 by Adam J. Engler, Christine C. Krieger, Christine Carag-Krieger +8 · 27 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Anatomy #Biochemistry #Biology #Cell #Cell biology #Cellular Mechanics and Interactions #Chemistry #Cytoskeleton #Embryonic heart #Embryonic stem cell #Extracellular matrix #Fibrosis #Matrix (chemical analysis) #Myocyte #Myofibril #Myofibroblast #Myosin #Pathology #Pluripotent Stem Cells Research #Regenerative medicine #Sarcomere #Stem cell #Tissue Engineering and Regenerative Medicine