Lars Klareskog

1. A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA–DR (shared epitope)–restricted immune reactions to autoantigens modified by citrullination
   2005/12/29 by Lars Klareskog, Patrik Stolt, Karin Lundberg +10 · 12 citations
   Medicine · Immunology and Microbiology · #Rheumatoid Arthritis Research and Therapies #Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis #Atherosclerosis and Cardiovascular Diseases
2. STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus
   2007/09/05 by Elaine F. Remmers, Robert M. Plenge, Annette T. Lee +20 · 8 citations
   Medicine · #Rheumatoid Arthritis Research and Therapies #Systemic Lupus Erythematosus Research #Cytokine Signaling Pathways and Interactions
3. Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis
   2006/02/28 by Eva Baecklund, Anastasia Iliadou, Johan Askling +8 · 4 citations
   Medicine · #Rheumatoid Arthritis Research and Therapies #Viral-associated cancers and disorders #Lymphoma Diagnosis and Treatment
4. Gene-Gene and Gene-Environment Interactions Involving HLA-DRB1, PTPN22, and Smoking in Two Subsets of Rheumatoid Arthritis
   2007/04/11 by Henrik Källberg, Leonid Padyukov, Robert M. Plenge +10 · 6 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Cytokine Signaling Pathways and Interactions #Diabetes and associated disorders #Rheumatoid Arthritis Research and Therapies
5. Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
   2019/12/01 by Phil H. Lee, Verneri Anttila, Hyejung Won +628 · 1 voice · 8 citations
   Biochemistry, Genetics and Molecular Biology · Psychology · #Genetic Associations and Epidemiology #Genomics and Rare Diseases #Obsessive-Compulsive Spectrum Disorders
6. European Population Substructure: Clustering of Northern and Southern Populations
   2006/09/12 by Michael F. Seldin, Russell Shigeta, Pablo Villoslada +6 · 5 citations
   Biochemistry, Genetics and Molecular Biology · #Genetic Associations and Epidemiology #Forensic and Genetic Research #Genetic Mapping and Diversity in Plants and Animals #Biology #Population #European population #Genetics #Founder effect #Single-nucleotide polymorphism #Population genetics #Evolutionary biology #SNP #Demography #Geography #Haplotype #Genotype
7. Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity
   2014/03/22 by Buhm Han, Dorothée Diogo, Steve Eyre +23 · 28 citations
   Immunology and Microbiology · Medicine · #Allele #Antigen #Biology #Gene #Genetics #Human leukocyte antigen #Immunology #Medicine #Monoclonal and Polyclonal Antibodies Research #Rheumatoid arthritis #Systemic Lupus Erythematosus Research #T-cell and B-cell Immunology
8. Rheumatoid arthritis
   2009/01/21 by Lars Klareskog, Anca I. Catrina, Anca Irinel Catrina +2 · 4 citations
   Medicine · #Autoimmune and Inflammatory Disorders Research #Rheumatoid Arthritis Research and Therapies #Systemic Lupus Erythematosus Research
9. Genetics of rheumatoid arthritis contributes to biology and drug discovery
   2013/12/24 by Yukinori Okada, Di Wu, Gosia Trynka +111 · 4 citations
   Medicine · #Chronic Lymphocytic Leukemia Research #Cytokine Signaling Pathways and Interactions #Monoclonal and Polyclonal Antibodies Research
10. Antibodies against citrullinated vimentin in rheumatoid arthritis: Higher sensitivity and extended prognostic value concerning future radiographic progression as compared with antibodies against cyclic citrullinated peptides
    2007/12/28 by Linda Mathsson, Mohammed Mullazehi, Marius C. Wick +4 · 4 citations
    Medicine · #Rheumatoid Arthritis Research and Therapies #Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis #Gout, Hyperuricemia, Uric Acid
11. A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides
    2014/02/15 by L Bossini-Castillo, Lara Bossini‐Castillo, Carolien G. F. de Kovel +67 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Antigen #Biology #Gene #Genetic Associations and Epidemiology #Genetic association #Genetics #Genome-wide association study #Genotype #Human leukocyte antigen #Immunology #Imputation (statistics) #Locus (genetics) #Medicine #Missing data #Population #Rheumatoid Arthritis Research and Therapies #Rheumatoid arthritis #Single-nucleotide polymorphism #Spondyloarthritis Studies and Treatments
12. Immunity to Citrullinated Proteins in Rheumatoid Arthritis
    2008/01/03 by Lars Klareskog, Johan Rönnelid, Karin Lundberg +2 · 4 citations
    Medicine · #Rheumatoid Arthritis Research and Therapies #Cell Adhesion Molecules Research #Monoclonal and Polyclonal Antibodies Research
13. A gene–environment interaction between smoking and shared epitope genes in HLA–DR provides a high risk of seropositive rheumatoid arthritis
    2004/10/01 by Leonid Padyukov, Camilla Silva, Patrik Stolt +2 · 2 citations
    Medicine · Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · #Rheumatoid Arthritis Research and Therapies #T-cell and B-cell Immunology #Diabetes and associated disorders
14. Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis
    2009/11/08 by Hiba Mahdi, Benjamin A Fisher, Benjamin A. Fisher +14 · 2 citations
    Immunology and Microbiology · Medicine · #Rheumatoid Arthritis Research and Therapies #Toxin Mechanisms and Immunotoxins #Viral Infections and Immunology Research
15. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
    2012/01/29 by Soumya Raychaudhuri, Cynthia Sandor, Eli A Stahl +19 · 2 citations
    Immunology and Microbiology · Medicine · #Rheumatoid Arthritis Research and Therapies #Systemic Lupus Erythematosus Research #T-cell and B-cell Immunology
16. Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: Observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Register cohorts
    2010/09/22 by Saedís Saevarsdóttir, Sara Wedrén, Maria Seddighzadeh +6 · 1 citation
    Medicine · #Rheumatoid Arthritis Research and Therapies #Hepatitis C virus research #Gout, Hyperuricemia, Uric Acid