Leonid Padyukov
- A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA–DR (shared epitope)–restricted immune reactions to autoantigens modified by citrullination
2005/12/29 by Lars Klareskog, Patrik Stolt, Karin Lundberg +10 · 12 citations
Medicine · Immunology and Microbiology · #Rheumatoid Arthritis Research and Therapies #Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis #Atherosclerosis and Cardiovascular Diseases
- STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus
2007/09/05 by Elaine F. Remmers, Robert M. Plenge, Annette T. Lee +20 · 7 citations
Medicine · #Rheumatoid Arthritis Research and Therapies #Systemic Lupus Erythematosus Research #Cytokine Signaling Pathways and Interactions
- Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity
2014/03/22 by Buhm Han, Dorothée Diogo, Steve Eyre +23 · 28 citations
Medicine · Immunology and Microbiology · #Systemic Lupus Erythematosus Research #Monoclonal and Polyclonal Antibodies Research #T-cell and B-cell Immunology
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
2019/12/01 by Phil H. Lee, Verneri Anttila, Hyejung Won +628 · 1 voice · 6 citations
Biochemistry, Genetics and Molecular Biology · Psychology · #Genetic Associations and Epidemiology #Genomics and Rare Diseases #Obsessive-Compulsive Spectrum Disorders
- Gene-Gene and Gene-Environment Interactions Involving HLA-DRB1, PTPN22, and Smoking in Two Subsets of Rheumatoid Arthritis
2007/04/11 by Henrik Källberg, Leonid Padyukov, Robert M. Plenge +10 · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cytokine Signaling Pathways and Interactions #Diabetes and associated disorders #Rheumatoid Arthritis Research and Therapies
- A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides
2014/02/15 by Lara Bossini‐Castillo, L Bossini-Castillo, C de Kovel +67 · 26 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Rheumatoid Arthritis Research and Therapies #Spondyloarthritis Studies and Treatments #Genetic Associations and Epidemiology
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
2013/12/24 by Yukinori Okada, Di Wu, Gosia Trynka +111 · 2 citations
Medicine · #Chronic Lymphocytic Leukemia Research #Cytokine Signaling Pathways and Interactions #Monoclonal and Polyclonal Antibodies Research
- Immunity to Citrullinated Proteins in Rheumatoid Arthritis
2008/01/03 by Lars Klareskog, Johan Rönnelid, Karin Lundberg +2 · 4 citations
Medicine · #Rheumatoid Arthritis Research and Therapies #Cell Adhesion Molecules Research #Monoclonal and Polyclonal Antibodies Research
- A gene–environment interaction between smoking and shared epitope genes in HLA–DR provides a high risk of seropositive rheumatoid arthritis
2004/10/01 by Leonid Padyukov, Camilla Silva, Patrik Stolt +2 · 2 citations
Medicine · Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · #Rheumatoid Arthritis Research and Therapies #T-cell and B-cell Immunology #Diabetes and associated disorders
- Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis
2009/11/08 by Hiba Mahdi, Benjamin A Fisher, Benjamin A. Fisher +14 · 2 citations
Immunology and Microbiology · Medicine · #Rheumatoid Arthritis Research and Therapies #Toxin Mechanisms and Immunotoxins #Viral Infections and Immunology Research
- Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
2012/01/29 by Soumya Raychaudhuri, Cynthia Sandor, Eli A. Stahl +19 · 2 citations
Immunology and Microbiology · Medicine · #Rheumatoid Arthritis Research and Therapies #Systemic Lupus Erythematosus Research #T-cell and B-cell Immunology