Richard A. Morgan
- T Lymphocyte-Directed Gene Therapy for ADA − SCID: Initial Trial Results After 4 Years
1995/10/20 by R. Michael Blaese, Kenneth W. Culver, A. Dusty Miller +21 · 39 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Adenosine #Adenosine deaminase #Adenosine deaminase deficiency #Biology #CAR-T cell therapy research #Gene #Genetic enhancement #Genetics #Immune system #Immunodeficiency #Immunology #Internal medicine #Lymphocyte #Medicine #RNA Interference and Gene Delivery #Severe combined immunodeficiency #Virology #Virus-based gene therapy research
- Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
2010/07/29 by James N. Kochenderfer, Wyndham H. Wilson, John E. Janik +12 · 39 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Adoptive cell transfer #Antibody #Antigen #B cell #Biology #Bone marrow #CAR-T cell therapy research #CD19 #Cancer research #Chimeric antigen receptor #Immune system #Immunology #Lymphoma #Medicine #Nanowire Synthesis and Applications #T cell #Viral Infectious Diseases and Gene Expression in Insects
- Gene Transfer into Humans — Immunotherapy of Patients with Advanced Melanoma, Using Tumor-Infiltrating Lymphocytes Modified by Retroviral Gene Transduction
1990/08/30 by Steven A. Rosenberg, Paul Aebersold, Kenneth Cornetta +12 · 6 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Virus-based gene therapy research #Cancer Research and Treatments #CAR-T cell therapy research
- Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes
2006/08/31 by Richard A. Morgan, Mark E. Dudley, John R. Wunderlich +13 · 5 citations
Medicine · Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · #CAR-T cell therapy research #Immunotherapy and Immune Responses #Virus-based gene therapy research
- Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia
2012/12/16 by Waleed Haso, Daniel W. Lee, Nirali N. Shah +10 · 5 citations
Medicine · Immunology and Microbiology · #CAR-T cell therapy research #Acute Lymphoblastic Leukemia research #Immune Cell Function and Interaction
- Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
2012/10/24 by Australian Pancreatic Cancer Genome Initiative, Andrew V. Biankin, Nicola Waddell +145 · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Cells and Metastasis #Cancer Genomics and Diagnostics #Pancreatic and Hepatic Oncology Research