Eric S. Lander
- Initial sequencing and analysis of the human genome
2001/02/01 by Eric S. Lander, Lauren Linton, Bruce W. Birren +97 · 78 citations
Biochemistry, Genetics and Molecular Biology · #RNA and protein synthesis mechanisms #Genomics and Phylogenetic Studies #Genomics and Chromatin Dynamics
- De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds
2017/03/24 by Olga Dudchenko, Sanjit Singh Batra, Sanjit S. Batra +9 · 192 citations
Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Genomics and Phylogenetic Studies #Chromosomal and Genetic Variations #Plant Virus Research Studies
- A Draft Sequence of the Neandertal Genome
2010/05/06 by Richard E. Green, Johannes Krause, Adrian W. Briggs +53 · 77 citations
Arts and Humanities · Biochemistry, Genetics and Molecular Biology · Social Sciences · #Forensic Anthropology and Bioarchaeology Studies #Forensic and Genetic Research #Pleistocene-Era Hominins and Archaeology
- The Cancer Genome Atlas Pan-Cancer analysis project
2013/09/01 by John N Weinstein, John N. Weinstein, Eric A Collisson +111 · 142 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Genomics and Diagnostics #Genetic factors in colorectal cancer #Lung Cancer Treatments and Mutations
- Genome sequence, comparative analysis and haplotype structure of the domestic dog
2005/12/01 by Broad Sequencing Platform members, Kerstin Lindblad-Toh, Claire M Wade +53 · 37 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Animal Genetics and Reproduction #Chromosomal and Genetic Variations #Genetic Mapping and Diversity in Plants and Animals
- Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005/09/30 by Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha +8 · 29 citations
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #RNA modifications and cancer #Gene expression and cancer classification
- Initial sequencing and comparative analysis of the mouse genome
2002/12/01 by Asif T. Chinwalla, Lisa L. Cook, Kimberly D. Delehaunty +97 · 23 citations
Biochemistry, Genetics and Molecular Biology · #Genomics and Chromatin Dynamics #Genomics and Phylogenetic Studies #RNA and protein synthesis mechanisms
- A comparative genomics multitool for scientific discovery and conservation
2020/11/11 by Diane P. Genereux, Aitor Serres, Joel Armstrong +45 · 1 voice · 31 citations
Biochemistry, Genetics and Molecular Biology · #Genomics and Phylogenetic Studies #Molecular Biology Techniques and Applications #Single-cell and spatial transcriptomics
- A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
2006/04/01 by Bradley E. Bernstein, B Bernstein, Tarjei S. Mikkelsen +13 · 15 citations
Biochemistry, Genetics and Molecular Biology · #Epigenetics and DNA Methylation #Genomics and Chromatin Dynamics #Pluripotent Stem Cells Research
- Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
2019/11/29 by Charles P. Fulco, Joseph Nasser, Thouis R. Jones +17 · 29 citations
Biochemistry, Genetics and Molecular Biology · #CRISPR and Genetic Engineering #Genomics and Chromatin Dynamics #RNA and protein synthesis mechanisms
- Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
2014/08/29 by Stephen K. Gire, Stephen Gire, Augustine Goba +69 · 37 citations
Medicine · #Viral Infections and Outbreaks Research #Viral Infections and Vectors #Zoonotic diseases and public health
- Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse
2005/01/01 by Bradley E. Bernstein, B Bernstein, Michael Kamal +12 · 8 citations
Biochemistry, Genetics and Molecular Biology · #Epigenetics and DNA Methylation #Genomics and Chromatin Dynamics #RNA modifications and cancer
- Positive Natural Selection in the Human Lineage
2006/06/15 by Pardis C. Sabeti, S. F. Schaffner, Ben Fry +7 · 7 citations
Biochemistry, Genetics and Molecular Biology · #Genetic Associations and Epidemiology #RNA and protein synthesis mechanisms #Genetic Mapping and Diversity in Plants and Animals
- Genome Sequence, Comparative Analysis, and Population Genetics of the Domestic Horse
2009/11/05 by Claire M. Wade, Elena Giulotto, Snævar Sigurðsson +55 · 4 citations
Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Genetic diversity and population structure #Genetic Mapping and Diversity in Plants and Animals #Chromosomal and Genetic Variations
- Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida
2006/10/18 by Sarah J. Bourlat, Thorhildur Juliusdottir, Christopher J. Lowe +13 · 4 citations
Agricultural and Biological Sciences · Earth and Planetary Sciences · Environmental Science · #Echinoderm biology and ecology #Marine Ecology and Invasive Species #Marine and coastal plant biology
- Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis
2008/12/09 by Haifeng Shao, Lindsay C. Burrage, David S. Sinasac +11 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Genetic Mapping and Diversity in Plants and Animals #Genetic and phenotypic traits in livestock #Genetics and Plant Breeding
- Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample
2024/07/01 by Marcela Sandoval‐Velasco, Olga Dudchenko, Juan Antonio Rodríguez +53 · 1 voice · 4 citations
Biochemistry, Genetics and Molecular Biology · #Genomics and Chromatin Dynamics #Genomics and Phylogenetic Studies #Molecular Biology Techniques and Applications
- Genetic association data are broadly consistent with stabilizing selection shaping human common diseases and traits
2024/06/23 by Evan Koch, Noah J Connally, Nikolas Baya +6 · 1 voice · 3 citations
Biochemistry, Genetics and Molecular Biology · #Genetic Associations and Epidemiology
- Describing Graphs: A First-Order Approach to Graph Canonization
1990/01/01 by Neil Immerman, Eric S. Lander, Eric Lander · 1 citation
Computer Science · Engineering · #Advanced Graph Theory Research #Formal Methods in Verification #VLSI and FPGA Design Techniques
- Positional specificity of different transcription factor classes within enhancers
2018/07/09 by Sharon R. Grossman, J Engreitz, John P. Ray +3 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Genomics and Chromatin Dynamics #RNA Research and Splicing #RNA modifications and cancer
- A Dictionary-Based Approach for Gene Annotation
1999/10/01 by Lior Pachter, Serafim Batzoglou, Valentin I. Spitkovsky +4 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Fractal and DNA sequence analysis #Machine Learning in Bioinformatics #Genomics and Phylogenetic Studies