Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations

2019/11/29 by Charles P. Fulco, Joseph Nasser, Thouis R. Jones +17 · 22 citations
Biochemistry, Genetics and Molecular Biology · #CRISPR and Genetic Engineering #Genomics and Chromatin Dynamics #RNA and protein synthesis mechanisms

paper · pdf · doi:10.1038/s41588-019-0538-0

openalex publication_date 2019/11/29 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Citations

• Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers

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