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Vamsi K. Mootha

  1. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    2005/09/30 by Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha +8 · 32 citations
    Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #RNA modifications and cancer #Gene expression and cancer classification
  2. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
    2011/06/17 by Joshua M. Baughman, Fabiana Perocchi, Hany S. Girgis +10 · 45 citations
    Biochemistry, Genetics and Molecular Biology · #Mitochondrial Function and Pathology #ATP Synthase and ATPases Research #RNA and protein synthesis mechanisms
  3. A genomic mutational constraint map using variation in 76,156 human genomes
    2023/12/06 by Siwei Chen, Laurent C. Francioli, Julia K. Goodrich +254 · 70 citations
    Biochemistry, Genetics and Molecular Biology · #Genomic variations and chromosomal abnormalities #Genomics and Chromatin Dynamics #Genomics and Rare Diseases
  4. MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
    2020/10/15 by Sneha Rath, Rohit Sharma, Rahul Gupta +29 · 35 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Proteomics Techniques and Applications #Metabolomics and Mass Spectrometry Studies #Mitochondrial Function and Pathology
  5. Lipoylation is dependent on the ferredoxin FDX1 and dispensable under hypoxia in human cells
    2023/07/20 by Pallavi R. Joshi, Shayan Sadre, Xiaoyan A. Guo +2 · 23 citations
    Medicine · Biochemistry, Genetics and Molecular Biology · #Adipose Tissue and Metabolism #Cancer, Hypoxia, and Metabolism #RNA modifications and cancer
  6. How many human proteoforms are there?
    2018/02/14 by Ruedi Aebersold, Jeffrey N. Agar, Jeffrey N Agar +87 · 2 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Proteomics Techniques and Applications #Bioinformatics and Genomic Networks #RNA and protein synthesis mechanisms