- IL‐10 derived from M2 macrophage promotes cancer stemness via JAK1/STAT1/NF‐κB/Notch1 pathway in non‐small cell lung cancer
2019/01/24 by Yang Li, Li Yang, Ying Dong +14 · 28 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Biology #Cancer #Cancer research #Cancer stem cell #Cell biology #Cytokine Signaling Pathways and Interactions #Epigenetics and DNA Methylation #Genetics #Immune cells in cancer #Immunology #In vitro #Inflammation #Internal medicine #Lung cancer #Macrophage #Medicine #NF-κB #Oncology #STAT1 #Signal transduction
- Severe acute respiratory syndrome coronavirus papain-like protease suppressed alpha interferon-induced responses through downregulation of extracellular signal-regulated kinase 1-mediated signalling pathways
2011/01/27 by Shih-Wein Li, Chien-Chen Lai, Chien‐Chen Lai +10 · 25 citations
Immunology and Microbiology · Medicine · #Biochemistry #Biology #Cell biology #Cytokine Signaling Pathways and Interactions #Downregulation and upregulation #Kinase #Molecular biology #Phosphorylation #Protein kinase A #SARS-CoV-2 and COVID-19 Research #STAT1 #Signal transduction #interferon and immune responses
- Activation of STAT3 by specific Gα subunits and multiple Gβγ dimers
2010/03/30 by Jessie Wai-Fong Yuen, Jessie W.F. Yuen, Lydia S.W. Poon +6 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Mathematics · Medicine · #Activator (genetics) #Biochemistry #Biology #Cell biology #Chemistry #Cytokine Signaling Pathways and Interactions #HER2/EGFR in Cancer Research #Phosphorylation #Protein Kinase Regulation and GTPase Signaling #Receptor #STAT protein #STAT1 #STAT2 #STAT3 #STAT4 #STAT5 #Signal transduction #stat
- A Point Mutation, E95D, in the Mumps Virus V Protein Disengages STAT3 Targeting from STAT1 Targeting
2009/04/23 by Mamta Puri, Ken Lemon, W. Paul Duprex +2 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cancer research #Cell biology #Gene #Genetics #Molecular biology #Mumps virus #Mutation #Point mutation #STAT1 #STAT3 #Signal transduction #Virology #Virology and Viral Diseases #Virus #Virus-based gene therapy research #vaccines and immunoinformatics approaches
- Rabies Viral Mechanisms to Escape the IFN System: The Viral Protein P Interferes with IRF-3, Stat1, and PML Nuclear Bodies
2006/05/01 by Mounira K. Chelbi‐Alix, Aurore Vidy, Jamila El Bougrini +1 · 1 citation
Immunology and Microbiology · Medicine · #interferon and immune responses #Viral Infections and Vectors #Herpesvirus Infections and Treatments #STAT1 #Interferon #Biology #Promyelocytic leukemia protein #Virology #Nuclear transport #Viral replication #Phosphorylation #Interferon regulatory factors #Antiviral protein #Nuclear protein #Gene #Cell biology #RNA #Transcription factor #Virus #Cytoplasm #Cell nucleus #Genetics