- Vascular smooth muscle ROCK1 contributes to hypoxia-induced pulmonary hypertension development in mice
2022/03/09 by Krishna C. Penumatsa, A. Singhal, Adit A. Singhal +12 · 3 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biology #Cell biology #Chemistry #Endocrinology #Hypoxia (environmental) #Internal medicine #Kinase #Medicine #Muscle hypertrophy #Oxygen #PI3K/AKT/mTOR signaling in cancer #Pharmacology #Protein Kinase Regulation and GTPase Signaling #Protein kinase A #Pulmonary Hypertension Research and Treatments #Pulmonary artery #Pulmonary hypertension #ROCK1 #ROCK2 #Rho-associated protein kinase #Right ventricular hypertrophy #Signal transduction
- The Rho Kinases: Critical Mediators of Multiple Profibrotic Processes and Rational Targets for New Therapies for Pulmonary Fibrosis
2014/11/14 by Rachel S. Knipe, Andrew M. Tager, James K. Liao · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin cytoskeleton #Biology #Cancer research #Cell #Cell biology #Cytoskeleton #Fibroblast Growth Factor Research #Fibrosis #Idiopathic pulmonary fibrosis #Immunology #Internal medicine #Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis #Kinase #Lung #Lung Cancer Treatments and Mutations #Medicine #Pathology #Protein kinase A #Pulmonary fibrosis #ROCK1 #ROCK2 #Rho-associated protein kinase