- Extrachromosomal DNA–Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN -Amplified Cancers
2025/08/07 by Giulia Montuori, Fengyu Tu, Di Qin +33 · 1 voice · 7 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cancer #Cancer Genomics and Diagnostics #Cancer research #Cell cycle #Copy-number variation #Extrachromosomal DNA #Gene #Gene dosage #Gene duplication #Gene expression #Genetics #Genome #Neuroblastoma Research and Treatments #Oncogene #Phenotype #Pluripotent Stem Cells Research
- TGF-β signaling pathway: Therapeutic targeting and potential for anti-cancer immunity
2013/12/01 by Shafat Ali, Muneeb U. Rehman, Ali Mohd Yatoo +7 · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Bone Metabolism and Diseases #Cancer #Cancer cell #Cancer research #Carcinogenesis #Cell biology #Cell cycle #Connective Tissue Growth Factor Research #Epidermal growth factor receptor #Metastasis #NF-κB Signaling Pathways #Oncogene #Pancreatic and Hepatic Oncology Research #R-SMAD #SMAD #Signal transduction #Stromal cell #TGF alpha #TGF-β signaling in diseases #Transforming growth factor
- Oestrogen and the enigmatic male predominance of gastric cancer
2008/08/27 by Evangelos Chandanos, Jesper Lagergren · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Breast cancer #Cancer #Endocrinology #Estrogen and related hormone effects #Gastric Cancer Management and Outcomes #Helicobacter pylori-related gastroenterology studies #Hormone #Incidence (geometry) #Internal medicine #Medicine #Oncogene #Oncology #Physiology #Prostate cancer #Tamoxifen
- Reactivation of liver-specific gene expression in an immortalized human hepatocyte cell line by introduction of the human HNF4α2 gene
2001/11/01 by Yasuhiro Inoue, Masahiro Miyazaki, Toshiya Tsuji +4 · 1 citation
Medicine · #Pancreatic function and diabetes #Pediatric Hepatobiliary Diseases and Treatments #Pancreatic and Hepatic Oncology Research #Transfection #Hepatocyte nuclear factor 4 #Molecular biology #Hepatocyte #Biology #Hepatocyte nuclear factors #Cell culture #Gene #Liver cell #Cell #Oncogene #Hep G2 #Immortalised cell line #Gene expression #Cell cycle #Transcription factor #Biochemistry #Genetics #In vitro #Internal medicine