- Programmable DNA Nanocages Enhance Levodopa Delivery for Neuroprotection in a Zebrafish Model of Parkinson's Disease
2026/08/04 by Krupa Kansara, Shubha Lakshmi Swain, Bhagyesh Parmae +4 · 1 voice
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Zebrafish Biomedical Research Applications #RNA Interference and Gene Delivery #Nuclear Receptors and Signaling #Neuroprotection #Nanocages #Parkin #Parkinsonism #MPTP #Zebrafish #PINK1 #Apoptosis #Dopamine
- MPTP‐induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF‐TrkB pathway
2015/01/05 by Guoqi Zhu, Junyao Li, Ling He +2 · 27 citations
Chemistry · Medicine · Neuroscience · Psychology · #Biochemistry #Brain-derived neurotrophic factor #Chemistry #Dopamine #Dopaminergic #Endocrinology #Glutamate receptor #Hippocampal formation #Internal medicine #Long-term potentiation #MPTP #Medicine #Memantine #NMDA receptor #Neuroscience #Neuroscience and Neuropharmacology Research #Neurotransmitter Receptor Influence on Behavior #Neurotrophic factors #Parkinson's Disease Mechanisms and Treatments #Pharmacology #Psychology #Receptor #Synaptic plasticity #Tropomyosin receptor kinase B
- Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease
2013/03/30 by Adalberto A. Castro, Bárbara P. Wiemes, Bárbara Paula Wiemes +9 · 13 citations
Medicine · Neuroscience · Psychology · #Alzheimer's disease research and treatments #Atorvastatin #Disease #Dopamine #Dopaminergic #Internal medicine #MPTP #Medicine #Motor coordination #Neuroprotection #Neuroscience #Nuclear Receptors and Signaling #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Pars compacta #Pharmacology #Psychology #Striatum #Substantia nigra
- Transgenic rodent models of Parkinson’s disease
2009/01/21 by B. K. Harvey, Y. Wang, Yue Wang +1 · 1 citation
Medicine · Neuroscience · #Biology #Cell biology #Disease #Dopamine #Dopaminergic #Gene #Genetically modified mouse #Genetics #Hydroxydopamine #Internal medicine #MPTP #Medicine #Mitochondrial biogenesis #Mitochondrion #Nerve injury and regeneration #Neurodegeneration #Neuroscience #Nuclear Receptors and Signaling #PINK1 #Parkin #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Phenotype #Respiratory chain #TFAM #Transgene
- Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis
1983/02/25 by J. William Langston, Philip L. Ballard, James W. Tetrud +1 · 1 citation
Chemistry · Medicine · Neuroscience · #Anesthesia #Chemistry #Disease #Drug #Epilepsy research and treatment #Internal medicine #MPTP #Medicine #Neuroscience and Neuropharmacology Research #Neurotoxin #Parkinson's disease #Parkinsonism #Pathological #Pharmacological Effects and Toxicity Studies #Pharmacology #Piperidine #Stereochemistry #Substantia nigra