- Emerging trends in genome integration tools for precision engineering of diverse bacterial species
2025/01/01 by Riesa K W Rohmat, Thea C T Irvine, Shivang Hina-Nilesh Joshi +5 · 3 voices
Biochemistry, Genetics and Molecular Biology · #Bacterial Genetics and Biotechnology #CRISPR and Genetic Engineering #Function (biology) #Gene Regulatory Network Analysis #Genome #Genome engineering #Genomics #Integrase #Prokaryote #Recombineering #Synthetic biology
- Screening of natural compounds from Cyperus rotundus Linn against SARS-CoV-2 main protease (Mpro): An integrated computational approach
2021/05/29 by S. Birendra Kumar, Swati Krishna, Sneha Pradeep +5 · 9 citations
Agricultural and Biological Sciences · Chemistry · Computer Science · Medicine · Pharmacology, Toxicology and Pharmaceutics · #ADME #Antiretroviral therapy #Biochemistry #Biology #Chemistry #Computational Drug Discovery Methods #Computational biology #Cyperus rotundus #Docking (animal) #Drug discovery #Drug-Induced Hepatotoxicity and Protection #Enzyme #Essential Oils and Antimicrobial Activity #Gene #In silico #Integrase #Medicine #Pharmacokinetics #Pharmacology #Protease #Ritonavir #Traditional medicine #Veterinary medicine #Viral load #Virology #Virus
- The structural biology of HIV-1: mechanistic and therapeutic insights
2012/03/16 by Alan Engelman, Peter Cherepanov · 1 citation
Immunology and Microbiology · Medicine · #Biology #Capsid #Cell biology #Computational biology #Cytomegalovirus and herpesvirus research #Gene #Genetics #HIV Research and Treatment #HIV/AIDS drug development and treatment #Human immunodeficiency virus (HIV) #Integrase #Lentivirus #RNA #Reverse transcriptase #Structural biology #Viral disease #Viral entry #Viral replication #Virology #Virus
- Antimicrobial resistance and distribution of sul genes and integron-associated intI genes among uropathogenic Escherichia coli in Queensland, Australia
2011/07/08 by Aycan Gündoğdu, Yuner Long, Ysanne Beverley Long +3 · 22 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Allele #Antibiotic Resistance in Bacteria #Antibiotic resistance #Antibiotics #Antimicrobial #Biology #Drug resistance #Escherichia coli #Escherichia coli research studies #Gene #Gene cassette #Genetics #Integrase #Integron #Microbiology #Phylogenetic tree #Urinary Tract Infections Management #Virology
- The Bacteroides fragilis Pathogenicity Island Is Contained in a Putative Novel Conjugative Transposon
2004/09/01 by Augusto A. Franco · 16 citations
Biochemistry, Genetics and Molecular Biology · #Bacteria #Bacterial Identification and Susceptibility Testing #Bacteroides #Bacteroides fragilis #Biology #Enterobacteriaceae and Cronobacter Research #Gene #Genetics #Genome #Genomics and Phylogenetic Studies #Insertion sequence #Integrase #Microbiology #Mobile genetic elements #Pathogenicity island #Plasmid #Transposable element #Transposase #Virulence
- Inhibitor design by wrapping packing defects in HIV-1 proteins
2004/08/02 by Ariel Fernández, Kristina Rogale, Ridgway Scott +1 · 1 citation
Chemistry · Immunology and Microbiology · Medicine · #Active site #Biochemistry #Biology #Biophysics #Catalysis #Chemistry #Click Chemistry and Applications #Combinatorial chemistry #DNA #Enzyme #HIV Research and Treatment #HIV-1 protease #HIV/AIDS drug development and treatment #Hydrogen bond #Integrase #Materials science #Molecule #Nanotechnology #Nucleophile #Organic chemistry #Protease #Protein engineering #Rational design #Stereochemistry
- Overexpression of the HIV-1 Gag-Pol Polyprotein Results in Intracellular Activation of HIV-1 Protease and Inhibition of Assembly and Budding of Virus-like Particles
1977/01/01 by Velissarios Karacostas, Elizabeth J. Wolffe, Kunio Nagashima +4 · 1 citation
Agricultural and Biological Sciences · Immunology and Microbiology · Medicine · #Bat Biology and Ecology Studies #Biochemistry #Biology #Enzyme #Erythrocyte Function and Pathophysiology #Gene #Genetics #Group-specific antigen #HIV Research and Treatment #HIV/AIDS drug development and treatment #Human immunodeficiency virus (HIV) #Integrase #Molecular biology #Monoclonal and Polyclonal Antibodies Research #Protease #RNA #Retrovirus #Reverse transcriptase #Virology #Virus