- Multi-modal refinement of the human heart atlas during the first gestational trimester
2025/02/10 by Christopher De Bono, Yichi Xu, Samina Kausar +14 · 1 voice · 5 citations
Biochemistry, Genetics and Molecular Biology · #Anatomy #Biology #Cell biology #Congenital heart defects research #Embryonic stem cell #Gene #Genetics #Heart development #Human heart #Internal medicine #RNA modifications and cancer #Single-cell and spatial transcriptomics
- Neddylation mediates ventricular chamber maturation through repression of Hippo signaling
2018/04/09 by Jianqiu Zou, Wenxia Ma, Jie Li +10 · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cell biology #Congenital heart defects research #Heart development #Hippo pathway signaling and YAP/TAZ #Hippo signaling pathway #Internal medicine #Medicine #NEDD8 #Neddylation #Signal transduction #Ubiquitin #Ubiquitin and proteasome pathways #Ubiquitin ligase
- Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development
2012/09/26 by Robert Opitz, Emilie Maquet, Jan Huisken +5 · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Anatomy #Animal Genetics and Reproduction #Biology #Birth, Development, and Health #Budding #Cell biology #Cellular differentiation #Congenital heart defects research #Embryo #Embryonic stem cell #Endocrinology #Endoderm #Foregut #Gene #Genetics #Green fluorescent protein #Heart development #Live cell imaging #Morphogenesis #Organogenesis #Pharyngeal pouch #Thyroid #Transgene #Zebrafish #mCherry
- Mechanisms of T-box gene function in the developing heart
2011/04/14 by Franziska Greulich, F. Greulich, C. Rudat +2 · 28 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Anatomy #Biology #Cardiac Fibrosis and Remodeling #Cardiology #Cell biology #Congenital heart defects research #Embryonic stem cell #Endocrinology #Gene #Gene expression #Genetics #Heart development #Internal medicine #Medicine #Mesoderm #Morphogenesis #Promoter #Sinoatrial node #Sinus venosus #TBX1 #Transcription factor #Wind Turbine Control Systems
- The sinus venosus progenitors separate and diversify from the first and second heart fields early in development
2010/01/28 by Mathilda T.M. Mommersteeg, Jorge N. Domínguez, Cornelia Wiese +7 · 27 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Anatomy #Biology #Cardiology #Congenital Heart Disease Studies #Congenital heart defects research #Developmental Biology and Gene Regulation #Genetics #Heart development #Internal medicine #Lateral plate mesoderm #Medicine #Mesoderm #Population #Sinus venosus
- Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity
2008/08/23 by Qing Ma, Bin Zhou, William T. Pu · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cardiac Fibrosis and Remodeling #Cell biology #Congenital heart defects research #Embryonic stem cell #Fate mapping #GATA4 #Gene #Gene expression #Genetics #Heart development #Progenitor #Progenitor cell #RNA and protein synthesis mechanisms #Reporter gene #Stem cell #Transcription factor
- Development of the proepicardial organ in the zebrafish
2007/10/29 by Fabrizio C. Serluca · 26 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Anatomy #Biology #Cell biology #Congenital heart defects research #Coronary Artery Anomalies #Electric Motor Design and Analysis #Embryonic stem cell #Gene #Gene knockdown #Genetics #Heart development #Lateral plate mesoderm #Mesoderm #Morphogenesis #Transcription factor #Zebrafish #Zinc finger #Zinc finger transcription factor
- BMP and FGF regulate the differentiation of multipotential pericardial mesoderm into the myocardial or epicardial lineage
2006/04/05 by Boudewijn P. T. Kruithof, Boudewijn P.T. Kruithof, Bram van Wijk +9 · 26 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Anatomy #Biology #Cell biology #Congenital heart defects research #Electric Motor Design and Analysis #Embryonic stem cell #Endocrinology #FGF and mesoderm formation #Fibroblast growth factor #Genetics #Heart development #Internal medicine #Lateral plate mesoderm #Lineage (genetic) #Medicine #Mesoderm #Pericardium #Receptor #Tissue Engineering and Regenerative Medicine
- Cardiac Chamber Formation: Development, Genes, and Evolution
2003/10/01 by ANTOON F. M. MOORMAN, Antoon F.M. Moorman, VINCENT M. CHRISTOFFELS +1 · 29 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Anatomy #Biology #Cardiac Ventricle #Cardiac cycle #Cardiac muscle #Cardiac pacemaker #Cardiomyopathy and Myosin Studies #Cell biology #Chordate #Congenital heart defects research #Coronary Artery Anomalies #Electrical conduction system of the heart #Electrocardiography #Embryonic heart #Embryonic stem cell #Gene #Genetics #Heart cells #Heart development #Internal medicine #Mammalian heart #Medicine #Myocyte #Neuroscience #Ventricle #Vertebrate
- Patterning the Embryonic Heart: Identification of Five Mouse Iroquois Homeobox Genes in the Developing Heart
2000/08/01 by Vincent M. Christoffels, Astrid G.M. Keijser, Arjan C. Houweling +2 · 27 citations
Biochemistry, Genetics and Molecular Biology · #Anatomy #Atrioventricular canal #Biology #Congenital heart defects research #DLX5 #Developmental Biology and Gene Regulation #Electrical conduction system of the heart #Electrocardiography #Embryonic heart #Embryonic stem cell #Endocardium #Endoderm #Gene #Gene expression #Genetics #Heart development #Heart disease #Homeobox #Homeobox protein Nkx-2.5 #Internal medicine #RNA Research and Splicing