Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity

2008/08/23 by Qing Ma, Bin Zhou, William T. Pu · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Congenital heart defects research #Cardiac Fibrosis and Remodeling #RNA and protein synthesis mechanisms

paper · doi:10.1016/j.ydbio.2008.08.013

Cited by

• Hox genes define distinct progenitor sub-domains within the second heart field
• Long-term labelling and tracing of endodermal cells using a perpetual cycling Gal4-UAS system
• Enhancer of zeste homolog 2 (Ezh2) is required in mouse Isl1-expressing progenitors for proper development of cardiac and skeletal hindlimb structures
• Epicardium and myocardium separate from a common precursor pool by crosstalk between bone morphogenetic protein- and fibroblast growth factor-signaling pathways. [europepmc]
• The role of secondary heart field in cardiac development. [europepmc]
• Genetic fate mapping demonstrates contribution of epicardium-derived cells to the annulus fibrosis of the mammalian heart. [europepmc]
• A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates. [europepmc]
• Origins of cardiac fibroblasts. [europepmc]
• Defining the earliest step of cardiovascular progenitor specification during embryonic stem cell differentiation. [europepmc]
• Hox genes define distinct progenitor sub-domains within the second heart field. [europepmc]
• Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation. [europepmc]
• Adult cardiac-resident MSC-like stem cells with a proepicardial origin. [europepmc]
• Polycomb repressive complex 2 regulates normal development of the mouse heart. [europepmc]
• Islet1 derivatives in the heart are of both neural crest and second heart field origin. [europepmc]
• Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease. [europepmc]
• Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. [europepmc]
• Genetic Cre-loxP assessment of epicardial cell fate using Wt1-driven Cre alleles. [europepmc]
• Heart field origin of great vessel precursors relies on nkx2.5-mediated vasculogenesis. [europepmc]
• Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development. [europepmc]
• Generation of the epicardial lineage from human pluripotent stem cells. [europepmc]
• Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity. [europepmc]
• Cellular origin and developmental program of coronary angiogenesis. [europepmc]
• A G-Rich Motif in the lncRNA Braveheart Interacts with a Zinc-Finger Transcription Factor to Specify the Cardiovascular Lineage. [europepmc]
• Cardiac Regeneration: Lessons From Development. [europepmc]
• Live imaging of heart tube development in mouse reveals alternating phases of cardiac differentiation and morphogenesis. [europepmc]
• Precardiac organoids form two heart fields via Bmp/Wnt signaling. [europepmc]
• Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement. [europepmc]
• Pre-existing beta cells but not progenitors contribute to new beta cells in the adult pancreas. [europepmc]