- Defining the Active Conformation of Typical Protein Kinase Domains from Substrate-Bound PDB Structures Enables Active-State AlphaFold2 Models for All 437 Human Catalytic Protein Kinases
2026/02/19 by Joan Gizzio, Bulat Faezov, Qifang Xu +1 · 1 voice
Biochemistry, Genetics and Molecular Biology · Computer Science · Materials Science · #Active site #Computational Drug Discovery Methods #Enzyme Structure and Function #Kinase #Protein Data Bank #Protein Data Bank (RCSB PDB) #Protein Structure and Dynamics #Protein engineering #Protein kinase A #Protein kinase domain #Protein structure #SH3 domain #c-Raf