Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

2016/05/02 by Marc Hafner, Mario Niepel, Mirra Chung +2 · 3 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · #Computational Drug Discovery Methods #Genomics and Chromatin Dynamics #Protein Degradation and Inhibitors

paper · doi:10.1038/nmeth.3853

crossref issued 2016/05/02 · crossref published 2016/05/02 · crossref published-online 2016/05/02 · openalex publication_date 2016/05/02 · crossref created 2016/05/02 · crossref published-print 2016/06/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01 · crossref indexed 2026/08/05

Citations

• Metrics other than potency reveal systematic variation in responses to cancer drugs
• Systematic identification of genomic markers of drug sensitivity in cancer cells
• Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

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• Multiplexed and reproducible high content screening of live and fixed cells using the Dye Drop method
• Peter Karl Sorger [wikipedia]