Biocatalytic asymmetric Mannich reaction of ketimines using wheat germ lipase

2016/01/01 by Lingling Wu, Yang Xiang, Da‐Cheng Yang +2 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · #Carbohydrate Chemistry and Synthesis #Cyclopropane Reaction Mechanisms #Enzyme Catalysis and Immobilization

paper · doi:10.1039/c5cy01923k

openalex publication_date 2016/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/28

Abstract

Wheat germ lipase (WGL) was used for the first time as a biocatalyst in asymmetric Mannich reaction of ketimines.

Citations

• Highly Diastereo‐ and Enantioselective Mannich Reactions of Synthetically Flexible Ketimines with Secondary Amine Organocatalysts
• Direct Organocatalytic Asymmetric Mannich Addition of 3‐Substituted‐2H‐1,4‐Benzoxazines: Access to Tetrasubstituted Carbon Stereocenters
• Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst
• A Novel Trypsin‐Catalyzed Three‐Component Mannich Reaction

Cited by

• Ketimine Mannich reaction [wikipedia]

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