2020/06/18 by Shuke Wu, Radka Šnajdrová, Jeffrey C. Moore +2 · 9 citations
Biochemistry, Genetics and Molecular Biology · Engineering · #Enzyme Catalysis and Immobilization #Microbial Metabolic Engineering and Bioproduction #Biofuel production and bioconversion
paper · doi:10.1002/anie.202006648
openalex publication_date 2020/06/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, biocatalysts are used on a large scale to make specialty and even bulk chemicals. This review intends to give illustrative examples in this field with a special focus on scalable chemical production using enzymes. It also discusses the opportunities and limitations of enzymatic syntheses using distinct examples and provides an outlook on emerging enzyme classes.