2010/05/18 by Barbara Zajc, Rakesh Kumar · 1 citation
Pharmacology, Toxicology and Pharmaceutics · Chemistry · #Fluorine in Organic Chemistry #Sulfur-Based Synthesis Techniques #Cyclopropane Reaction Mechanisms
paper · doi:10.1055/s-0029-1218789
openalex publication_date 2010/05/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
The Julia-Kocienski olefination provides a versatile platform for the synthesis of fluorovinyl compounds. This review describes our efforts as well as those of others in the synthesis of various fluorinated aryl and heteroaryl sulfones and their utility as olefination reagents for the modular assembly of fluoroalkenes. Where data is available, the influence of the fluorine atom on the reactivity of the olefination reagents and the stereochemical outcome of the olefination are described.