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Bridging to Transplant: TDM-guided Outpatient Dalbavancin Therapy in Chronic Granulomatous Disease With Deep-seeded Inoperable Abscesses Over 11 Months

2025/04/28 by Micha Banz, Stefan Hagel, Fritz Sörgel +4 · 1 voice
Medicine · Immunology and Microbiology · #Antifungal resistance and susceptibility #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Antimicrobial Resistance in Staphylococcus

paper · doi:10.1093/ofid/ofaf260

openalex publication_date 2025/04/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

Therapeutic drug monitoring facilitated the successful outpatient use of low-dosage dalbavancin for treating inoperable staphylococcal abscesses in a patient with chronic granulomatous disease. This approach minimized adverse effects and allowed for effective infection control, highlighting its potential role in complex infectious cases requiring long-term antimicrobial therapy.

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