The Use of Oritavancin as Consolidation Therapy for Infective Endocarditis Caused by Enterococcus spp.

2025/07/30 by Federico Frondizi, Gabriele Maria Leanza, Marta Chiuchiarelli +7 · 2 voices
Medicine · Biochemistry, Genetics and Molecular Biology · #Infective Endocarditis Diagnosis and Management #Antimicrobial Resistance in Staphylococcus #Bacterial Identification and Susceptibility Testing

paper · pdf · doi:10.1093/ofid/ofaf416

openalex publication_date 2025/07/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

Oritavancin is emerging as a potential alternative to standard antibiotic regimens in the treatment of infective endocarditis caused by gram-positive bacteria, though evidence remains limited. We hereby report 7 cases of enterococcal endocarditis treated with oritavancin as consolidation therapy, resulting in 6 cures and 1 relapse.

Citations

• Real-world evidence of dalbavancin effectiveness as consolidation therapy in infective endocarditis due to Enterococcus spp.

Discussions

• The Use of Oritavancin as Consolidation Therapy for Infective Endocarditis Caused by Enterococcus spp. ✅ Just Accepted #IDSky [bsky, 2 points, 0 comments]
• Long-acting lipoglycopeptides can provide a convenient alternative to daily antibiotic infusions for enterococcal endocarditis. doi.org/10.1093/ofid... PraediAlert can help you monitor OPAT patient [bsky, 1 points, 0 comments]

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