New thiazolidine-2,4-diones as potential anticancer agents and apoptotic inducers targeting VEGFR-2 kinase: Design, synthesis, in silico and in vitro studies

2024/03/22 by Hazem Elkady, Hazem A. Mahdy, Mohammed S. Taghour +10 · 18 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Angiogenesis and VEGF in Cancer #Apoptosis #Biochemistry #Biology #Cancer #Cancer cell #Cancer research #Cell culture #Cell cycle #Cell growth #Chemistry #Cytotoxicity #Docking (animal) #IC50 #In silico #In vitro #Kinase #MTT assay #Medicine #PI3K/AKT/mTOR signaling in cancer #Pharmacology #Sorafenib #Stereochemistry #Synthesis and biological activity #Thiazolidine

paper · doi:10.1016/j.bbagen.2024.130599

published in Biochimica et Biophysica Acta (BBA) - General Subjects 1868(6), 130599 (Elsevier BV)

openalex publication_date 2024/03/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Citations

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