Robert W. Mahley

1. Ancient human genomes suggest three ancestral populations for present-day Europeans
   2013/12/31 by Iosif Lazaridis, Nick Patterson, Alissa Mittnik +140 · 172 citations
   Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genetic diversity and population structure #Genomics and Phylogenetic Studies #q-bio.PE
2. Apolipoprotein E: Far More Than a Lipid Transport Protein
   2000/09/01 by Robert W. Mahley, Stanley C. Rall · 14 citations
   Medicine · Biochemistry, Genetics and Molecular Biology · #Lipoproteins and Cardiovascular Health #Alzheimer's disease research and treatments #Peroxisome Proliferator-Activated Receptors #Gene isoform #Apolipoprotein E #Allele #Biology #Genetics #Locus (genetics) #Apolipoprotein B #Alzheimer's disease #Lipoprotein #Disease #Gene #Endocrinology #Internal medicine #Cholesterol #Medicine
3. Plasma lipoproteins: apolipoprotein structure and function.
   1984/12/01 by Robert W. Mahley, T L Innerarity, S C Rall +1 · 13 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Cancer, Lipids, and Metabolism #Diabetes, Cardiovascular Risks, and Lipoproteins #Lipoproteins and Cardiovascular Health #Apolipoprotein B #Lipoprotein #Biochemistry #Apolipoprotein C2 #Apolipoprotein E #Lipid metabolism #Metabolism #Chemistry #Function (biology) #Biology #Very low-density lipoprotein #Cholesterol #Genetics #Internal medicine #Medicine
4. Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site.
   1982/03/01 by K H Weisgraber, Karl H. Weisgraber, T L Innerarity +2 · 8 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Amino acid #Arginine #Binding site #Biochemistry #Chemistry #Cysteine #Enzyme #Glycosylation and Glycoproteins Research #Peptidase Inhibition and Analysis #Protease and Inhibitor Mechanisms #Receptor
5. Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
   1988/04/29 by Robert W. Mahley · 7 citations
   Medicine · Biochemistry, Genetics and Molecular Biology · Chemistry · #Lipoproteins and Cardiovascular Health #Diabetes, Cardiovascular Risks, and Lipoproteins #Cancer, Lipids, and Metabolism #Apolipoprotein B #Cholesterol #Apolipoprotein E #Apolipoprotein C2 #Lipoprotein #Reverse cholesterol transport #Receptor #Internal medicine #Endocrinology #LDL receptor #High-density lipoprotein #Biology #Cell biology #Chemistry #Very low-density lipoprotein #Medicine #Disease
6. Complete protein sequence and identification of structural domains of human apolipoprotein B
   1986/10/01 by Timothy J. Knott, T. J. Knott, R. J. Pease +30 · 6 citations
   Chemistry · Medicine · #Apolipoprotein B #Apolipoprotein E #Biochemistry #Biology #Catabolism #Chemistry #Cholesterol #Cholesterol and Lipid Metabolism #Cholesteryl ester #Diabetes, Cardiovascular Risks, and Lipoproteins #Endocrinology #Intermediate-density lipoprotein #Internal medicine #LDL receptor #Lipoprotein #Lipoproteins and Cardiovascular Health #Low-density lipoprotein #Medicine #Metabolism #Triglyceride #Very low-density lipoprotein
7. Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS
   2008/12/23 by Robert W. Mahley, Karl H. Weisgraber, Yadong Huang · 5 citations
   Medicine · Neuroscience · #Alzheimer's disease research and treatments #Lipoproteins and Cardiovascular Health #Diabetes, Cardiovascular Risks, and Lipoproteins #Apolipoprotein E #Disease #Pathological #Genetic predisposition #Apolipoprotein B #Biology #Lipoprotein #Allele #Risk factor #Receptor #Stressor #Mechanism (biology) #Alzheimer's disease #Host factor #Immunology #Medicine #Genetics #Internal medicine #Cholesterol #Neuroscience #Gene #Virus #Endocrinology
8. Turkish Population Structure and Genetic Ancestry Reveal Relatedness among Eurasian Populations
   2012/02/15 by Uğur Hodoğlugil, Robert W. Mahley · 4 citations
   Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genetic diversity and population structure #Genetic and phenotypic traits in livestock #Genetic structure #Turkish #Genetic diversity #Principal component analysis #Population #Evolutionary biology #Geography #Demography #Phylogenetic tree #Population structure #Central asia #Biology #Ancestry-informative marker #Genetics #Genotype #Allele frequency #Statistics #Gene
9. Three-Dimensional Structure of the LDL Receptor-Binding Domain of Human Apolipoprotein E
   1991/06/28 by Charles B. Wilson, Mark R. Wardell, Karl H. Weisgraber +2 · 2 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Computer Science · Medicine · #Apolipoprotein B #Apolipoprotein E #Biochemistry #Biology #Biophysics #Chemistry #Cholesterol #Computational Drug Discovery Methods #Crystallography #Helix (gastropod) #Helix bundle #Internal medicine #LDL receptor #Leucine zipper #Lipoprotein #Lipoproteins and Cardiovascular Health #Peptide sequence #Plasma protein binding #Protein Structure and Dynamics #Protein structure #Receptor
10. Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders
    2016/06/09 by Robert W. Mahley · 2 citations
11. Nucleotide sequence and structure of the human apolipoprotein E gene.
    1985/05/01 by Young‐Ki Paik, David J. Chang, Catherine A. Reardon +3 · 3 citations
    Chemistry · Biochemistry, Genetics and Molecular Biology · #Advanced Proteomics Techniques and Applications #Lipid metabolism and biosynthesis #Ubiquitin and proteasome pathways
12. Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro , and the APOE ε4/ε4 genotype accelerates HIV disease progression
    2008/06/18 by Trevor D. Burt, Brian K. Agan, Vincent C. Marconi +9 · 3 citations
    Immunology and Microbiology · Medicine · #HIV Research and Treatment #Alzheimer's disease research and treatments #HIV-related health complications and treatments #Apolipoprotein E #Genotype #Disease #Biology #Immunology #Dementia #Alzheimer's disease #Neurodegeneration #Apolipoprotein B #Virology #Medicine #Genetics #Internal medicine #Cholesterol #Endocrinology #Gene
13. IMPLIKASI HARGA BBM TERHADAP PERILAKU KONSUMSI RUMAH TANGGA DI KAWASAN SUBURBAN SPRAWL KOTA SEMARANG
    2004/01/01 by Yadong Huang, Karl H. Weisgraber, Lennart Mucke +3 · 1 citation
    Computer Science · Engineering · Medicine · Neuroscience · #Alzheimer's disease #Alzheimer's disease research and treatments #Apolipoprotein E #Art #Biology #Cholinesterase and Neurodegenerative Diseases #Computational Drug Discovery Methods #Disease #Humanities #Medicine #Neurochemistry #Neurology #Neuroscience #Pathological #Pathology #Urban Transport Systems Analysis
14. Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E
    1999/01/01 by Robert W. Mahley, Zhong-Sheng Ji · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · Chemistry · #Diabetes, Cardiovascular Risks, and Lipoproteins #Lipid metabolism and disorders #Lipid metabolism and biosynthesis #Chylomicron #Apolipoprotein E #Catabolism #Apolipoprotein B #Chemistry #Lipoprotein lipase #Cell biology #Receptor #Perisinusoidal space #LDL receptor #Lipoprotein #Internal medicine #Endocrinology #Biochemistry #Biology #Hepatocyte #Very low-density lipoprotein #Cholesterol #Metabolism #In vitro #Enzyme #Medicine