Tiinamaija Tuomi

1. A genomic mutational constraint map using variation in 76,156 human genomes
   2023/12/06 by Siwei Chen, Laurent C. Francioli, Julia K. Goodrich +254 · 71 citations
   Biochemistry, Genetics and Molecular Biology · #Genomic variations and chromosomal abnormalities #Genomics and Chromatin Dynamics #Genomics and Rare Diseases
2. Genetic Similarities Between Latent Autoimmune Diabetes in Adults, Type 1 Diabetes, and Type 2 Diabetes
   2008/03/01 by Camilla Cervin, Valeriya Lyssenko, E. Bakhtadze +5 · 4 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · Immunology and Microbiology · #Diabetes and associated disorders #Pancreatic function and diabetes #T-cell and B-cell Immunology #TCF7L2 #Type 2 diabetes #Diabetes mellitus #Medicine #PTPN22 #Type 1 diabetes #Genotype #Internal medicine #Human leukocyte antigen #Endocrinology #Allele #Immunology #Single-nucleotide polymorphism #Biology #Gene #Genetics #Antigen
3. Latent Autoimmune Diabetes in Adults Differs Genetically From Classical Type 1 Diabetes Diagnosed After the Age of 35 Years
   2010/08/30 by Mette K. Andersen, Virve Lundgren, Joni A. Turunen +5 · 4 citations
   Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Diabetes and associated disorders #T-cell and B-cell Immunology #Pancreatic function and diabetes #Medicine #PTPN22 #Type 1 diabetes #Internal medicine #Diabetes mellitus #Type 2 diabetes #Endocrinology #Quartile #Genotype #Autoimmune diabetes #Human leukocyte antigen #Single-nucleotide polymorphism #Immunology #Genetics #Antigen #Biology #Gene #Confidence interval
4. Effects of Common Genetic Variants Associated With Type 2 Diabetes and Glycemic Traits on α- and β-Cell Function and Insulin Action in Humans
   2013/04/05 by Anna Jonsson, Claes Ladenvall, Tarunveer S. Ahluwalia +10 · 26 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Action (physics) #Biology #Diabetes mellitus #Diet, Metabolism, and Disease #Endocrinology #Function (biology) #Genetic Associations and Epidemiology #Genetics #Glycemic #Insulin #Internal medicine #Liver Disease Diagnosis and Treatment #Medicine #Type 2 diabetes
5. The genetic architecture of type 2 diabetes
   2016/07/11 by Christian Fuchsberger, Jason Flannick, Tanya M. Teslovich +314 · 2 citations
   Biochemistry, Genetics and Molecular Biology · #Allele #Allele frequency #Bioinformatics and Genomic Networks #Biology #DNA sequencing #Diabetes mellitus #Epigenetics and DNA Methylation #Exome #Exome sequencing #Gene #Genetic Associations and Epidemiology #Genetic architecture #Genetic association #Genetics #Genome #Genome-wide association study #Genotype #Genotyping #Heritability #Imputation (statistics) #Minor allele frequency #Missing data #Missing heritability problem #Mutation #Quantitative trait locus #Single-nucleotide polymorphism #Type 2 diabetes #Whole genome sequencing
6. Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes
   2014/06/06 by Mette K. Andersen, Maria Sterner, Tom Forsén +9 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · #Antibody #Autoantibody #Autoimmune diabetes #Biology #Diabetes and associated disorders #Diabetes mellitus #Endocrinology #Gene #Genetic Associations and Epidemiology #Genetics #Genome-wide association study #Genotype #Immunology #Internal medicine #Medicine #Pancreatic function and diabetes #Single-nucleotide polymorphism #TCF7L2 #Type 1 diabetes #Type 2 diabetes
7. Antibodies to Glutamic Acid Decarboxylase Reveal Latent Autoimmune Diabetes Mellitus in Adults With a Non—Insulin-Dependent Onset of Disease
   1993/02/01 by Tiinamaija Tuomi, Leif Groop, Paul Zimmet +3 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · #Diabetes and associated disorders #Pancreatic function and diabetes #Diabetes Management and Research #Insulitis #Diabetes mellitus #Insulin #Medicine #Internal medicine #Autoantibody #Glutamate decarboxylase #Endocrinology #Islet #Pathogenesis #Antibody #Autoimmune disease #Disease #Immunology #Biology #Enzyme
8. First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes
   2018/09/25 by Diana L. Cousminer, Emma Ahlqvist, Rajashree Mishra +60 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · #Diabetes and associated disorders #Pancreatic function and diabetes #Diabetes Management and Research #Medicine #Type 1 diabetes #Type 2 diabetes #Diabetes mellitus #Autoimmune diabetes #Genome-wide association study #Population #Autoimmunity #Human leukocyte antigen #Autoimmune disease #Immunology #Disease #Bioinformatics #Single-nucleotide polymorphism #Immune system #Internal medicine #Genetics #Endocrinology #Biology #Genotype #Gene #Antigen