Albert C. Ludolph

1. Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
   2022/09/21 by Timothy M. Miller, Jonathan Mill, Merit E. Cudkowicz +27 · 55 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Amyotrophic Lateral Sclerosis Research #Biology #Chemistry #Computational biology #Computer science #Gene #Genetics #Molecular biology #Neurogenetic and Muscular Disorders Research #Oligonucleotide #RNA Research and Splicing
2. Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis
   2013/06/19 by Johannes Brettschneider, Kelly Del Tredici, Jon B. Toledo +17 · 6 citations
3. Grey-matter abnormalities in boys with Tourette syndrome: magnetic resonance imaging study using optimised voxel-based morphometry
   2006/04/28 by Andrea G. Ludolph, Freimut D. Juengling, Gerhard Libal +3 · 22 citations
   Medicine · Neuroscience · Psychology · #Autism Spectrum Disorder Research #Grey matter #Magnetic resonance imaging #Medicine #Neuroscience #Obsessive-Compulsive Spectrum Disorders #Psychiatry #Psychology #Putamen #Radiology #Tourette syndrome #Voxel #Voxel-based morphometry #White matter
4. An observational study on quality of life and preferences to sustain life in locked-in state
   2019/08/07 by Magdalena Kuźma‐Kozakiewicz, Magdalena Kuzma-Kozakiewicz, Peter M. Andersen +8 · 26 citations
   Medicine · Neuroscience · Psychology · #Amyotrophic Lateral Sclerosis Research #Cerebral Palsy and Movement Disorders #Genetic Neurodegenerative Diseases #Gerontology #Internal medicine #Medicine #Observational study #Psychology #Psychotherapist #Quality of life (healthcare)
5. Deficits in verbal fluency in presymptomatic C9orf72 mutation gene carriers—a developmental disorder
   2020/08/27 by Dorothée E Lulé, Dorothée Lulé, Hans-Peter Müller +13 · 26 citations
   Medicine · Neuroscience · Psychology · #Amyotrophic Lateral Sclerosis Research #Amyotrophic lateral sclerosis #Audiology #C9orf72 #Clinical psychology #Cognition #Dementia #Disease #Fractional anisotropy #Frontotemporal dementia #Hereditary Neurological Disorders #Internal medicine #Magnetic resonance imaging #Medicine #Neurogenetic and Muscular Disorders Research #Neuropsychology #Neuroscience #Psychology #Verbal fluency test #White matter
6. Poly‐GP in cerebrospinal fluid links C9orf72‐associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD
   2017/04/13 by Carina Lehmer, Patrick Oeckl, Jochen H. Weishaupt +29 · 3 citations
   Medicine · Neuroscience · #Amyotrophic Lateral Sclerosis Research #Genetic Neurodegenerative Diseases #Neurogenetic and Muscular Disorders Research
7. Epidemiology of amyotrophic lateral sclerosis in Southern Germany
   2017/02/20 by Angela Rosenbohm, The ALS Registry Study Group, Raphael S. Peter +5 · 1 citation
   Medicine · Neuroscience · #Amyotrophic Lateral Sclerosis Research #Neurogenetic and Muscular Disorders Research #Neurological diseases and metabolism
8. Exploratory Tau PET/CT with [11C]PBB3 in Patients with Suspected Alzheimer’s Disease and Frontotemporal Lobar Degeneration: A Pilot Study on Correlation with PET Imaging and Cerebrospinal Fluid Biomarkers
   2024/07/01 by Joachim Strobel, Elham Yousefzadeh‐Nowshahr, Katharina Deininger +13 · 1 voice · 1 citation
   Medicine · Neuroscience · #Medical Imaging Techniques and Applications #Advanced MRI Techniques and Applications #Functional Brain Connectivity Studies
9. Body weight is a robust predictor of clinical progression in Huntington disease
   2017/08/05 by Jorien M.M. van der Burg, Sarah L. Gardiner, Albert C. Ludolph +3 · 1 citation
   Neuroscience · Biochemistry, Genetics and Molecular Biology · Medicine · #Genetic Neurodegenerative Diseases #Mitochondrial Function and Pathology #Neurological disorders and treatments
10. Cognitive impairment in patients with multiple system atrophy and progressive supranuclear palsy
    2010/06/24 by Richard G. Brown, Lucette Lacomblez, G. Bernhard Landwehrmeyer +9 · 1 citation
    Medicine · Neuroscience · Psychology · #Alzheimer's disease research and treatments #Atrophy #Clinical Dementia Rating #Cognition #Cognitive impairment #Dementia #Developmental psychology #Disease #Executive dysfunction #Internal medicine #Medicine #Neurological disorders and treatments #Neuropsychology #Neuroscience #Parkinson's Disease Mechanisms and Treatments #Pediatrics #Progressive supranuclear palsy #Pseudobulbar palsy #Psychiatry #Psychology #Rating scale
11. Alternative splicing of the 5′‐sequences of the mouse EAAT2 glutamate transporter and expression in a transgenic model for amyotrophic lateral sclerosis
    2002/07/24 by Christoph Münch, M. Ebstein, Ulrich Seefried +6 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Alternative splicing #Amyotrophic Lateral Sclerosis Research #Amyotrophic lateral sclerosis #Biology #Cell biology #Disease #Gene #Gene expression #Genetically modified mouse #Genetics #Glutamate receptor #Internal medicine #Medicine #Messenger RNA #Neurogenetic and Muscular Disorders Research #Neuroscience #RNA #RNA Research and Splicing #RNA splicing #Receptor #Transgene
12. Riluzole in Huntington's disease: a 3‐year, randomized controlled study
    2007/08/13 by G. Bernhard Landwehrmeyer, Bruno Dubois, Justo Garcı́a de Yébenes +8 · 1 citation
    Neuroscience · Medicine · Biochemistry, Genetics and Molecular Biology · #Genetic Neurodegenerative Diseases #Amyotrophic Lateral Sclerosis Research #RNA Research and Splicing
13. Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression
    2017/11/15 by Petra Steinacker, Federico Verde, Lubin Fang +27 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · #Amyotrophic Lateral Sclerosis Research #Amyotrophic lateral sclerosis #Central nervous system disease #Cerebrospinal fluid #Degenerative disease #Dementia #Differential diagnosis #Disease #Frontotemporal dementia #Frontotemporal lobar degeneration #Immunohistochemistry #Immunology #Inflammation #Internal medicine #Medicine #Microglia #Neurofilament #Pathology #Spinal Cord Injury Research #Spinal cord #Studies on Chitinases and Chitosanases
14. Differential pattern of brain‐specific CSF proteins tau and amyloid‐beta in Parkinsonian syndromes
    2010/06/29 by Sigurd D. Süßmuth, Ingo Uttner, G. Bernhard Landwehrmeyer +10 · 1 citation
    Medicine · Psychology · #Alzheimer's disease #Alzheimer's disease research and treatments #Atrophy #Biochemistry #Biology #Biomarker #Central nervous system disease #Cerebrospinal fluid #Degenerative disease #Disease #Endocrinology #Glial fibrillary acidic protein #Immunohistochemistry #Internal medicine #Medicine #Neurodegeneration #Neurological disorders and treatments #Parkinson's Disease Mechanisms and Treatments #Parkinsonism #Pathology #Progressive supranuclear palsy #Psychology #Tau protein
15. Pathological TDP-43 changes in Betz cells differ from those in bulbar and spinal α-motoneurons in sporadic amyotrophic lateral sclerosis
    2016/10/18 by Heiko Braak, Albert C. Ludolph, Manuela Neumann +2 · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · #Amyotrophic Lateral Sclerosis Research #Neurogenetic and Muscular Disorders Research #Prion Diseases and Protein Misfolding
16. Konsortium zur Erforschung der frontotemporalen Lobärdegeneration
    2011/07/29 by M. Otto, Markus Otto, A.C. Ludolph +16 · 1 citation
    Medicine · Neuroscience · Psychology · #Alzheimer's disease research and treatments #Amyotrophic Lateral Sclerosis Research #Amyotrophic lateral sclerosis #Aphasia #Corticobasal degeneration #Dementia #Disease #Frontotemporal dementia #Frontotemporal lobar degeneration #Medicine #Neurological diseases and metabolism #Neuroscience #Pathology #Primary progressive aphasia #Progressive supranuclear palsy #Psychology #Semantic dementia