Markus Otto
- The cryo-electron microscopy structure of huntingtin
2018/02/21 by Qiang Guo, Bin Huang, Jingdong Cheng +12 · 1 voice · 8 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Genetic Neurodegenerative Diseases #Mitochondrial Function and Pathology #Muscle Physiology and Disorders
- Neurofilaments as biomarkers in neurological disorders
2018/08/31 by Michael Khalil, Charlotte E. Teunissen, Markus Otto +12 · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Amyotrophic Lateral Sclerosis Research #Kruppel-like factors research #Skin and Cellular Biology Research
- Poly‐GP in cerebrospinal fluid links C9orf72‐associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD
2017/04/13 by Carina Lehmer, Patrick Oeckl, Jochen H. Weishaupt +29 · 3 citations
Medicine · Neuroscience · #Amyotrophic Lateral Sclerosis Research #Genetic Neurodegenerative Diseases #Neurogenetic and Muscular Disorders Research
- Frequency and Longitudinal Course of Behavioral and Neuropsychiatric Symptoms in Participants With Genetic Frontotemporal Dementia
2024/09/16 by Sonja Schönecker, Francisco J. Martínez-Murcia, Francisco J. Martinez-Murcia +50 · 6 citations
Medicine · #Amyotrophic Lateral Sclerosis Research #Dementia and Cognitive Impairment Research #Alzheimer's disease research and treatments
- Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease
2024/07/11 by Lorenzo Barba, Samir Abu-Rumeileh, Samir Abu‐Rumeileh +9 · 17 citations
Medicine · Neuroscience · Psychology · #Alzheimer's disease #Alzheimer's disease research and treatments #Biology #Cognitive decline #Context (archaeology) #Dementia #Dementia with Lewy bodies #Disease #Ginkgo biloba and Cashew Applications #Lewy body #Medicine #Neurodegeneration #Neuroimaging #Neuropathology #Neuroscience #Parkinson's Disease Mechanisms and Treatments #Pathological #Pathology #Prodromal Stage #Psychology
- Exploratory Tau PET/CT with [11C]PBB3 in Patients with Suspected Alzheimer’s Disease and Frontotemporal Lobar Degeneration: A Pilot Study on Correlation with PET Imaging and Cerebrospinal Fluid Biomarkers
2024/07/01 by Joachim Strobel, Elham Yousefzadeh‐Nowshahr, Katharina Deininger +13 · 1 voice · 1 citation
Medicine · Neuroscience · #Medical Imaging Techniques and Applications #Advanced MRI Techniques and Applications #Functional Brain Connectivity Studies
- Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression
2017/11/15 by Petra Steinacker, Federico Verde, Lubin Fang +27 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Amyotrophic Lateral Sclerosis Research #Amyotrophic lateral sclerosis #Central nervous system disease #Cerebrospinal fluid #Degenerative disease #Dementia #Differential diagnosis #Disease #Frontotemporal dementia #Frontotemporal lobar degeneration #Immunohistochemistry #Immunology #Inflammation #Internal medicine #Medicine #Microglia #Neurofilament #Pathology #Spinal Cord Injury Research #Spinal cord #Studies on Chitinases and Chitosanases
- Differential pattern of brain‐specific CSF proteins tau and amyloid‐beta in Parkinsonian syndromes
2010/06/29 by Sigurd D. Süßmuth, Ingo Uttner, G. Bernhard Landwehrmeyer +10 · 1 citation
Medicine · Psychology · #Alzheimer's disease #Alzheimer's disease research and treatments #Atrophy #Biochemistry #Biology #Biomarker #Central nervous system disease #Cerebrospinal fluid #Degenerative disease #Disease #Endocrinology #Glial fibrillary acidic protein #Immunohistochemistry #Internal medicine #Medicine #Neurodegeneration #Neurological disorders and treatments #Parkinson's Disease Mechanisms and Treatments #Parkinsonism #Pathology #Progressive supranuclear palsy #Psychology #Tau protein
- Specific serum and CSF microRNA profiles distinguish sporadic behavioural variant of frontotemporal dementia compared with Alzheimer patients and cognitively healthy controls
2018/05/10 by Johannes Denk, Felix Oberhauser, Johannes Kornhuber +12 · 1 citation
Medicine · Neuroscience · #Alzheimer's disease research and treatments #Neuroinflammation and Neurodegeneration Mechanisms #Dementia and Cognitive Impairment Research
- Konsortium zur Erforschung der frontotemporalen Lobärdegeneration
2011/07/29 by M. Otto, Markus Otto, Albert C. Ludolph +16 · 1 citation
Medicine · Neuroscience · Psychology · #Alzheimer's disease research and treatments #Amyotrophic Lateral Sclerosis Research #Amyotrophic lateral sclerosis #Aphasia #Corticobasal degeneration #Dementia #Disease #Frontotemporal dementia #Frontotemporal lobar degeneration #Medicine #Neurological diseases and metabolism #Neuroscience #Pathology #Primary progressive aphasia #Progressive supranuclear palsy #Psychology #Semantic dementia