Ryan Faucette
- A phase 1 study investigating DX-2930 in healthy subjects
2014/06/26 by Yung Chyung, Bradley Vince, Ryan Iarrobino +8 · 3 citations
Medicine · Immunology and Microbiology · #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Complement system in diseases #Hemophilia Treatment and Research #Medicine #Pharmacokinetics #Placebo #Tolerability #Adverse effect #Pharmacodynamics #Internal medicine #Pharmacology #Gastroenterology #Pathology
- Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody
2014/06/26 by Jon Kenniston, Ryan Faucette, Diana Martik +18 · 2 citations
Medicine · Chemistry · #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Blood Coagulation and Thrombosis Mechanisms #Peptidase Inhibition and Analysis #Kallikrein #High-molecular-weight kininogen #Kininogen #Bradykinin #Prekallikrein #Chemistry #Serine protease #Hereditary angioedema #Zymogen #Serpin #C1-inhibitor #Pharmacology #Molecular biology #Internal medicine #Biochemistry #Angioedema #Immunology #Protease #Medicine #Biology #Enzyme #Receptor
- Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis
2017/02/17 by Aleena Banerji, Paula J. Busse, Mustafa M. Shennak +25 · 2 citations
Medicine · Immunology and Microbiology · #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Complement system in diseases #Hemophilia Treatment and Research #Hereditary angioedema #Angioedema #Medicine #C1-inhibitor #Kallikrein #Placebo #Adverse effect #Bradykinin #Gastroenterology #High-molecular-weight kininogen #Internal medicine #Tolerability #Kininogen #Pharmacology #Anesthesia #Immunology #Pathology