Paul A. Northcott
- DNA methylation-based classification of central nervous system tumours
2018/03/13 by David Capper, David T. W. Jones, David Jones +155 · 68 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Glioma Diagnosis and Treatment #Epigenetics and DNA Methylation #Cancer Genomics and Diagnostics
- Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
2020/02/05 by Ruibin Xi, Dhawal Jain, Youngsook L. Jung +1341 · 16 citations
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases
- Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes
2019/05/10 by Tanvi Sharma, Edward C. Schwalbe, Ed C. Schwalbe +24 · 29 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Bioinformatics #Biology #Cancer Genomics and Diagnostics #Computational biology #Concordance #Epigenetics and DNA Methylation #Genetics #Glioma Diagnosis and Treatment #Internal medicine #Medicine #Medulloblastoma #Meta-analysis #Oncology
- Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
2015/03/09 by Andrey Korshunov, Marina Ryzhova, Volker Hovestadt +19 · 28 citations
Medicine · #Astrocytoma #Biology #CDKN2A #Cancer research #DNA methylation #Gene #Genetics #Glioma #Glioma Diagnosis and Treatment #IDH1 #Internal medicine #Medicine #Methylation #Mutation #Neuroblastoma Research and Treatments #Oncology #Pancreatic and Hepatic Oncology Research #Pathology #Pleomorphic xanthoastrocytoma
- Molecular subgroups of medulloblastoma: the current consensus
2011/12/02 by Michael D. Taylor, Paul A. Northcott, Andrey Korshunov +13 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Genomics and Diagnostics #Epigenetics and DNA Methylation #Glioma Diagnosis and Treatment
- Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
2014/03/01 by Marcel Kool, David Jones, David T.W. Jones +103 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Chromatin Remodeling and Cancer #Genomics and Chromatin Dynamics #Hedgehog Signaling Pathway Studies