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Ludmil B. Alexandrov

  1. The repertoire of mutational signatures in human cancer
    2020/02/05 by PCAWG Mutational Signatures Working Group, Erik N. Bergstrom, Arnoud Boot +76 · 49 citations
    Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Evolution and Genetic Dynamics #Genomics and Rare Diseases
  2. Pan-cancer analysis of whole genomes
    2020/02/05 by Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse +97 · 50 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Genomics and Diagnostics #Cancer-related Molecular Pathways #Genetic factors in colorectal cancer
  3. Mutational Processes Molding the Genomes of 21 Breast Cancers
    2012/05/01 by Serena Nik‐Zainal, Serena Nik-Zainal, Ludmil B. Alexandrov +76 · 22 citations
    Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Genomic variations and chromosomal abnormalities #Genomics and Chromatin Dynamics
  4. Nonnegative/Binary matrix factorization with a D-Wave quantum annealer
    2017/04/05 by Daniel O’Malley, Daniel O'Malley, Velimir V. Vesselinov +2 · 1 voice · 7 citations
    Computer Science · Engineering · #Neural Networks and Reservoir Computing #Optical Network Technologies #Quantum Computing Algorithms and Architecture #cs.LG #quant-ph #stat.ML
  5. Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
    2020/02/05 by Ruibin Xi, Dhawal Jain, Youngsook L. Jung +1341 · 10 citations
    Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases
  6. RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia
    2014/01/12 by Elli Papaemmanuil, Inmaculada Rapado, Yilong Li +50 · 3 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Acute Lymphoblastic Leukemia research #Acute Myeloid Leukemia Research #Cancer Genomics and Diagnostics
  7. Long-Term Latency of Highly Mutated Cells in Normal Mouse Skin Is Reversed by Exposure to Tumor Promoters and Chronic Tissue Damage
    2025/03/12 by Yun Rose Li, Eve Kandyba, Kyle Halliwill +13 · 1 voice · 1 citation
    Biochemistry, Genetics and Molecular Biology · Mathematics · Medicine · #Cancer Research and Treatments #Cancer, Stress, Anesthesia, and Immune Response #Mathematical Biology Tumor Growth
  8. Geographic and age variations in mutational processes in colorectal cancer
    2025/04/23 by Marcos Díaz‐Gay, Wellington dos Santos, Sarah Moody +60 · 1 voice · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · #Genetic factors in colorectal cancer #Cancer Genomics and Diagnostics #Colorectal Cancer Treatments and Studies