Serena Nik-Zainal
- Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
2011/01/01 by Philip J. Stephens, Chris Greenman, Chris D. Greenman +39 · 22 citations
Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Genomic variations and chromosomal abnormalities #Cancer Genomics and Diagnostics #Chromosomal and Genetic Variations
- Mutational Processes Molding the Genomes of 21 Breast Cancers
2012/05/01 by Serena Nik‐Zainal, Serena Nik-Zainal, Ludmil B. Alexandrov +76 · 17 citations
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Genomic variations and chromosomal abnormalities #Genomics and Chromatin Dynamics
- Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
2020/02/05 by Ruibin Xi, Dhawal Jain, Youngsook L. Jung +1341 · 8 citations
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases
- RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia
2014/01/12 by Elli Papaemmanuil, Inmaculada Rapado, Yilong Li +50 · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Acute Lymphoblastic Leukemia research #Acute Myeloid Leukemia Research #Cancer Genomics and Diagnostics
- Ductal carcinoma in situ: to treat or not to treat, that is the question
2019/07/08 by Maartje van Seijen, on behalf of the PRECISION team, Esther H. Lips +12 · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Breast Cancer Treatment Studies #Cancer Genomics and Diagnostics #Esophageal Cancer Research and Treatment