Lauri A. Aaltonen
- The repertoire of mutational signatures in human cancer
2020/02/05 by PCAWG Mutational Signatures Working Group, Erik N. Bergstrom, Arnoud Boot +76 · 41 citations
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Evolution and Genetic Dynamics #Genomics and Rare Diseases
- Pan-cancer analysis of whole genomes
2020/02/05 by Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse +97 · 42 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Genomics and Diagnostics #Cancer-related Molecular Pathways #Genetic factors in colorectal cancer
- Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
2020/02/05 by Ruibin Xi, Dhawal Jain, Youngsook L. Jung +1341 · 8 citations
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases
- Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
2022/12/20 by Ceres Fernández–Rozadilla, Ceres Fernandez-Rozadilla, Maria Timofeeva +254 · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Colorectal Cancer Screening and Detection #Genetic Associations and Epidemiology #Genetic factors in colorectal cancer
- Inherited mutations affecting the SRCAP complex are central in moderate-penetrance predisposition to uterine leiomyomas
2023/02/10 by Niko Välimäki, Vilja Jokinen, Tatiana Cajuso +11 · 8 citations
Medicine · #Uterine Myomas and Treatments #Ovarian cancer diagnosis and treatment #Cardiac tumors and thrombi