Peter Kilford
- Hepatocellular Binding of Drugs: Correction for Unbound Fraction in Hepatocyte Incubations Using Microsomal Binding or Drug Lipophilicity Data
2008/04/15 by Peter Kilford, Peter J. Kilford, Michael Gertz +2 · 3 citations
Chemistry · Mathematics · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Biochemistry #Biology #Chemistry #Drug #Drug Transport and Resistance Mechanisms #Drug metabolism #Extrapolation #Hepatocyte #In vitro #In vivo #Lipophilicity #Liver Disease Diagnosis and Treatment #Mathematics #Microsome #Pharmacogenetics and Drug Metabolism #Pharmacology
- Prediction of Drug Clearance by Glucuronidation from in Vitro Data: Use of Combined Cytochrome P450 and UDP-Glucuronosyltransferase Cofactors in Alamethicin-Activated Human Liver Microsomes
2008/10/03 by Peter J. Kilford, Peter Kilford, Rowan Stringer +3 · 1 citation
Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Alamethicin #Analytical Chemistry and Chromatography #Biochemistry #Chemistry #Cofactor #Cytochrome #Cytochrome P450 #Drug Transport and Resistance Mechanisms #Drug metabolism #Enzyme #Glucuronidation #Glucuronosyltransferase #Human liver #In vitro #Isozyme #Membrane #Microsoma #Microsome #Oxazepam #Pharmacogenetics and Drug Metabolism