- Targeting factor XI and factor XIa to prevent thrombosis
2023/12/24 by David Gailani, Andras Gruber, András Gruber · 19 citations
Medicine · Nursing · #Apixaban #Atrial fibrillation #Blood Coagulation and Thrombosis Mechanisms #Clotting factor #Coagulation #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Discovery and development of direct thrombin inhibitors #Hemostasis #Intensive care medicine #Internal medicine #Medicine #Pharmacology #Platelet #Rivaroxaban #Thrombin #Thrombosis #Vitamin K Research Studies #Warfarin
- Direct oral anticoagulants and venous thromboembolism
2016/08/31 by Massimo Franchini, Pier Mannuccio Mannucci · 1 citation
Medicine · #Venous Thromboembolism Diagnosis and Management #Atrial Fibrillation Management and Outcomes #Blood Coagulation and Thrombosis Mechanisms #Medicine #Edoxaban #Rivaroxaban #Dabigatran #Apixaban #Deep vein #Direct thrombin inhibitor #Pulmonary embolism #Intensive care medicine #Narrative review #Thrombosis #Venous thromboembolism #Discovery and development of direct thrombin inhibitors #Anticoagulant #Venous thrombosis #Warfarin #Internal medicine #Atrial fibrillation #Thrombin
- Thrombomodulin as an intravascular safeguard against inflammatory and thrombotic diseases
2015/11/11 by Takashi Ito, Yasuyuki Kakihana, Ikuro Maruyama · 1 citation
Medicine · Immunology and Microbiology · #Blood Coagulation and Thrombosis Mechanisms #Complement system in diseases #Blood properties and coagulation #Thrombomodulin #Anticoagulant #Protein C #Thrombin #Inflammation #Medicine #Coagulation #Immunology #Platelet #Internal medicine
- Assessing the Methodology for Calculating Platelet Contribution to Clot Strength (Platelet Component) in Thromboelastometry and Thrombelastography
2015/09/18 by Cristina Solomon, Marco Ranucci, Gerald Hochleitner +2 · 25 citations
Medicine · #Anesthesia #Antiplatelet Therapy and Cardiovascular Diseases #Biomedical engineering #Clot retraction #Composite material #Elasticity (physics) #Fibrin #Fibrinogen #Immunology #Internal medicine #Materials science #Medicine #Platelet #Thrombelastography #Thrombin #Thromboelastometry #Trauma, Hemostasis, Coagulopathy, Resuscitation #Venous Thromboembolism Diagnosis and Management
- Fibrinolysis and the control of blood coagulation
2014/09/16 by John C. Chapin, John Chapin, Katherine A. Hajjar · 2 citations
Chemistry · Medicine · #Biochemistry #Blood Coagulation and Thrombosis Mechanisms #Blood properties and coagulation #Chemistry #Coagulation #Enzyme #Fibrin #Fibrinogen #Fibrinolysis #Hemostasis #Immunology #Internal medicine #Medicine #Plasmin #Platelet #Platelet Disorders and Treatments #Thrombin #Thrombus
- Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation
2014/03/25 by Éric Boilard, Eric Boilard, Guillaume Paré +6 · 29 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Coagulation #Diabetes and associated disorders #Immune system #Immune thrombocytopenia #Immunology #Influenza A virus #Influenza Virus Research Studies #Internal medicine #Medicine #Monoclonal and Polyclonal Antibodies Research #Platelet #Thrombin #Thrombin generation #Virology #Virus
- Mechanisms of Thrombus Formation
2008/08/27 by Bruce Furie, Barbara C. Furie · 5 citations
Medicine · #Blood Coagulation and Thrombosis Mechanisms #Antiplatelet Therapy and Cardiovascular Diseases #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Medicine #Extravasation #Thrombus #Hemostasis #Fibrin #Coagulation #Circulatory system #Thrombin #Tissue factor #Blood vessel #Platelet #Pathology #Cardiology #Surgery #Internal medicine #Immunology
- Activation of Platelet Function Through G Protein–Coupled Receptors
2006/12/07 by Stefan Offermanns · 30 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Antiplatelet Therapy and Cardiovascular Diseases #Biochemistry #Biology #Cell biology #Chemistry #G protein #G protein-coupled receptor #Hemostasis #Immunology #Internal medicine #Medicine #Platelet #Platelet Disorders and Treatments #Platelet activation #Platelet adhesiveness #Platelet aggregation #Protease-activated receptor #Receptor #Receptor Mechanisms and Signaling #Signal transduction #Thrombin #Thromboxane #Thromboxane A2 #Thrombus
- Platelet-rich Plasmas: Growth Factor Content and Roles in Wound Healing
2005/05/01 by J.-P. Fréchette, Julien Fréchette, Isabelle Martineau +3 · 25 citations
Chemistry · Medicine · #Biochemistry #Biology #Cell #Cell biology #Chemistry #Endocrinology #Epidermal growth factor #Fetal bovine serum #Growth factor #Immunology #In vitro #Internal medicine #Medicine #Osteoblast #Periodontal Regeneration and Treatments #Platelet #Platelet-rich plasma #Receptor #Tendon Structure and Treatment #Thrombin #Transforming growth factor #Umbilical vein #VEGF receptors #Vascular endothelial growth factor #Wound Healing and Treatments #Wound healing
- Triabin, a Highly Potent Exosite Inhibitor of Thrombin
1995/12/01 by Christiane Noeske-Jungblut, Christiane Noeske‐Jungblut, Bernard Haendler +7 · 27 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Benzamidine #Biochemical and Structural Characterization #Biochemistry #Biology #Chemistry #Discovery and development of direct thrombin inhibitors #Enzyme #Immunology #Molecular biology #Partial thromboplastin time #Platelet #Signaling Pathways in Disease #Thrombin #Thrombin time #Thrombomodulin #Venomous Animal Envenomation and Studies
- The Nature and Significance of Platelet Products in Human Plasma
1967/05/01 by Peter Wolf · 36 citations
Chemistry · Medicine · #Biochemistry #Biology #Biophysics #Blood properties and coagulation #Chemistry #Clot retraction #Coagulation #Fibrinogen #Genital Health and Disease #Immunology #Internal medicine #Medicine #Platelet #Platelet Disorders and Treatments #Thrombin
- Blood coagulation in fish
1962/11/01 by Russell F. Doolittle, Douglas M. Surgenor · 2 citations
Chemistry · Environmental Science · Medicine · #Biochemistry #Biology #Blood Coagulation and Thrombosis Mechanisms #Blood properties and coagulation #Chemistry #Coagulation #Endocrinology #Fibrinogen #Fibrinolysis #Fish <Actinopterygii> #Fish biology, ecology, and behavior #Hagfish #Internal medicine #Medicine #Platelet #Thrombin