- Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds
2011/03/26 by Mario Caruana, Tobias Högen, Johannes Levin +4 · 25 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Alpha-synuclein #Biochemical and biochemical processes #Biochemistry #Biology #Chemistry #Disease #Dopamine #Dopaminergic #Gene #Ginkgo biloba and Cashew Applications #Internal medicine #Medicine #Missense mutation #Mutation #Neuroscience #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Pars compacta #Pathogenesis #Substantia nigra #Synuclein #Synucleinopathies
- Ubiquitination of α-Synuclein in Lewy Bodies Is a Pathological Event Not Associated with Impairment of Proteasome Function
2003/11/01 by George K. Tofaris, Azam Razzaq, Bernardino Ghetti +2 · 32 citations
Chemistry · Medicine · Neuroscience · #Alpha-synuclein #Biochemistry #Biology #Cell biology #Chemistry #Dementia #Dementia with Lewy bodies #Disease #Enzyme #Immunohistochemistry #Lewy body #Lysosomal Storage Disorders Research #Medicine #Neurological diseases and metabolism #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Pathology #Proteasome #Proteolysis #Synuclein #Synucleinopathies #Ubiquitin
- α-Synuclein Is Degraded by Both Autophagy and the Proteasome
2003/06/29 by Julie L. Webb, Brinda Ravikumar, Jane T. Atkins +3 · 40 citations
Chemistry · Medicine · Neuroscience · #Alpha-synuclein #Apoptosis #Autophagy #Autophagy in Disease and Therapy #Biochemistry #Biology #Cell biology #Chemistry #Dementia with Lewy bodies #Disease #Dopamine #Dopaminergic #Immunology #Medicine #Nerve injury and regeneration #Neuroscience #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Pathogenesis #Pathology #Proteasome #Substantia nigra #Synuclein
- Stabilization of α-Synuclein Secondary Structure upon Binding to Synthetic Membranes
1998/04/01 by W. Sean Davidson, Ana Jonas, David F. Clayton +1 · 44 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Alpha-synuclein #Alzheimer's disease research and treatments #Biochemistry #Biology #Biophysics #Cell biology #Cellular transport and secretion #Chemistry #Membrane #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Phospholipid #Synuclein #Vesicle