- High false sign rates in transcriptome-wide association studies
2025/12/20 by Peter Alexander Gerlach, Nikhil Milind, Jeffrey Spence +1 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · #Association (psychology) #Bioinformatics and Genomic Networks #Covariate #False discovery rate #Genetic Associations and Epidemiology #Genetic Mapping and Diversity in Plants and Animals #Haplotype #Multiple comparisons problem #Sign (mathematics) #Spurious relationship
- What Have We (Not) Learnt from Millions of Scientific Papers with P Values?
2019/03/20 by John P. A. Ioannidis · 29 citations
Decision Sciences · Economics, Econometrics and Finance · Mathematics · Psychology · #Artificial intelligence #Bayesian inference #Bayesian probability #Biology #Causal inference #Computer science #Confidence interval #Confounding #Econometrics #False discovery rate #Frequentist inference #Health Systems, Economic Evaluations, Quality of Life #Inference #MEDLINE #Mathematics #Meta-analysis and systematic reviews #Multiple comparisons problem #Null hypothesis #Psychology #Significance testing #Statistical Methods in Clinical Trials #Statistical hypothesis testing #Statistical inference #Statistics #p-value
- Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates
2015/11/05 by Anders Eklund, Thomas Nichols, Thomas E. Nichols +1 · 1 voice · 4 citations
Mathematics · Medicine · Neuroscience · #Advanced MRI Techniques and Applications #Artificial intelligence #Biology #Cluster (spacecraft) #Computer science #Data mining #False discovery rate #Functional Brain Connectivity Studies #Inference #Magnetic resonance imaging #Mathematics #Medicine #Multiple comparisons problem #Neural dynamics and brain function #Nonparametric statistics #Parametric statistics #Pattern recognition (psychology) #Permutation (music) #Resampling #Statistical hypothesis testing #Statistical inference #Statistical parametric mapping #Statistics #Voxel #math.ST #stat.AP #stat.CO #stat.ME #stat.TH
- Multivariate multidistance tests for high-dimensional low sample size case-control studies
2015/01/29 by Marco Marozzi · 1 citation
Mathematics · #Statistical Methods and Inference #Statistical Methods in Clinical Trials #Statistical Methods and Bayesian Inference #Multivariate statistics #Sample size determination #Multiple comparisons problem #Multivariate analysis #Statistics #Sample (material) #Mathematics #Computer science #Physics
- Multivariate tests based on interpoint distances with application to magnetic resonance imaging
2014/04/17 by Marco Marozzi · 2 citations
Mathematics · #Advanced Statistical Methods and Models #Statistical Methods and Inference #Statistical Distribution Estimation and Applications #Consistency (knowledge bases) #Mathematics #Normality #Normality test #Sample size determination #Multivariate statistics #Multivariate normal distribution #Statistical hypothesis testing #Statistics #Sample (material) #Multiple comparisons problem #Test (biology) #Applied mathematics #Algorithm
- P-Value Precision and Reproducibility
2011/11/01 by Dennis D. Boos, Leonard A. Stefanski · 30 citations
Computer Science · Decision Sciences · Mathematics · #Artificial intelligence #Computer science #Context (archaeology) #Contrast (vision) #Data Analysis with R #Econometrics #Geography #Mathematics #Meta-analysis and systematic reviews #Multiple comparisons problem #Null hypothesis #Replicate #Reproducibility #Rounding #Sample (material) #Sample size determination #Statistical Methods in Clinical Trials #Statistical hypothesis testing #Statistical power #Statistical significance #Statistics #Value (mathematics) #p-value
- Type I error rate control for testing many hypotheses: a survey with proofs
2010/12/18 by Etienne Roquain, Étienne Roquain, Roquain, Etienne · 1 citation
Decision Sciences · Mathematics · #Binomial distribution #Computer science #Econometrics #FOS: Computer and information sciences #False discovery rate #Independence (probability theory) #Mathematical proof #Mathematics #Methodology (stat.ME) #Multiple comparisons problem #Optimal Experimental Design Methods #Quantile #Statistical Methods and Bayesian Inference #Statistical Methods in Clinical Trials #Statistical hypothesis testing #Statistics #Type I and type II errors #stat.ME
- Why we (usually) don't have to worry about multiple comparisons
2009/07/15 by Andrew Gelman, Jennifer Hill, Gelman, Andrew +3 · 2 voices · 10 citations
Decision Sciences · Mathematics · Psychology · #Artificial intelligence #Bayesian probability #Computer science #Data mining #Econometrics #Hierarchical database model #Mathematics #Multilevel model #Multiple comparisons problem #Optimal Experimental Design Methods #Perspective (graphical) #Pooling #Psychology #Statistical Methods and Bayesian Inference #Statistical Methods in Clinical Trials #Statistics #Type I and type II errors #Worry #stat.AP #stat.ME
- Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
2005/08/03 by J Li, Jin Li, L Ji +1 · 47 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · #Algorithm #Biology #Computer science #Correlation #Eigenvalues and eigenvectors #False discovery rate #Gene expression and cancer classification #Genetic Associations and Epidemiology #Genetics #Mathematics #Matrix (chemical analysis) #Multiple comparisons problem #Permutation (music) #Statistical Methods in Clinical Trials #Statistical hypothesis testing #Statistics #Type I and type II errors
- A Comparison of Case‐Control and Family‐Based Association Methods: The Example of Sickle‐Cell and Malaria
2005/04/05 by Hans Ackerman, H. Ackerman, S. Usen +9 · 26 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · Medicine · #Allele #Biology #Case-control study #Computer science #Confidence interval #Demography #Disease #Environmental health #Genetic Associations and Epidemiology #Genetics #Haplotype #Hemoglobinopathies and Related Disorders #Internal medicine #Malaria Research and Control #Mathematics #Medicine #Multiple comparisons problem #Odds ratio #Population #Sickle cell trait #Statistics #Trait #Transmission disequilibrium test
- The positive false discovery rate: a Bayesian interpretation and the q-value
2003/12/01 by John D. Storey · 1 citation
Mathematics · #Statistical Methods in Clinical Trials #Statistical Methods and Bayesian Inference #Advanced Statistical Methods and Models #False discovery rate #Mathematics #Multiple comparisons problem #Bayesian probability #False positive paradox #Statistical hypothesis testing #Statistics #Posterior probability #p-value #Value (mathematics) #Prior probability #Econometrics
- Statistical significance for genomewide studies
2003/07/25 by John D. Storey, Robert Tibshirani · 145 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · #Artificial intelligence #Biology #Computational biology #Computer science #Data mining #False discovery rate #False positive paradox #False positive rate #False positives and false negatives #Feature (linguistics) #Gene #Gene expression and cancer classification #Genetic Associations and Epidemiology #Genetics #Genome #Genomics and Chromatin Dynamics #Linkage (software) #Mathematics #Measure (data warehouse) #Multiple comparisons problem #Null hypothesis #Set (abstract data type) #Statistical hypothesis testing #Statistics
- A sharper Bonferroni procedure for multiple tests of significance
1988/01/01 by Yosef Hochberg, YOSEF HOCHBERG · 116 citations
Decision Sciences · Mathematics · #Bonferroni correction #Computer science #Library science #Mathematics #Multiple comparisons problem #Optimal Experimental Design Methods #Statistical Methods and Bayesian Inference #Statistical Methods in Clinical Trials #Statistical significance #Statistics #Tel aviv
- A Multiple Testing Procedure for Clinical Trials
1979/09/01 by Peter C. O’Brien, Peter C. O'Brien, Thomas R. Fleming · 91 citations
Decision Sciences · Mathematics · Medicine · #Chi-square test #Computer science #Mathematics #Medicine #Meta-analysis and systematic reviews #Multiple comparisons problem #Optimal Experimental Design Methods #Sample size determination #Statistic #Statistical Methods in Clinical Trials #Statistical hypothesis testing #Statistics #Test (biology) #Test statistic