- Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
2014/04/25 by John P Guilinger, John P. Guilinger, David B. Thompson +3 · 5 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced biosensing and bioanalysis techniques #Allele #Biology #CRISPR #CRISPR and Genetic Engineering #Cas9 #Chemistry #Chromosomal and Genetic Variations #Computational biology #FokI #Gene #Genetics #Genome #Genome editing #Molecular biology #Nuclease
- TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
2010/08/10 by Ting Li, Sheng Huang, Wen Zhi Jiang +4 · 5 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #CRISPR and Genetic Engineering #Cell biology #DNA #DNA Repair Mechanisms #Effector #Endonuclease #FokI #Gene #Genetics #Genome #Genome editing #Homologous recombination #In vitro recombination #Molecular biology #Molecular cloning #Non-homologous end joining #Peptide sequence #Plant Virus Research Studies #Restriction enzyme #Transcription activator-like effector nuclease