Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

2014/04/25 by John P. Guilinger, John P Guilinger, David B. Thompson +3 · 5 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Advanced biosensing and bioanalysis techniques #CRISPR and Genetic Engineering #Chromosomal and Genetic Variations

paper · doi:10.1038/nbt.2909

crossref issued 2014/04/25 · crossref published 2014/04/25 · crossref published-online 2014/04/25 · openalex publication_date 2014/04/25 · crossref created 2014/04/25 · crossref published-print 2014/06/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · crossref indexed 2026/07/26 · openalex updated_date 2026/07/28

Citations

• A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Cited by

• History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology
• Plant genome editing with TALEN and CRISPR
• Genome-editing Technologies for Gene and Cell Therapy
• Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9
• FokI [wikipedia]